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Rx Item-Hydrocortisone-Pramoxine 2.5% 1% Cream 1 Oz By Perrigo Gen Analpram HC

Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Hydrocortisone-Pramoxine 2.5% 1% Cream 1 Oz By Perrigo Gen Analpram HC

$157.21$89.99

Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649, Rx Item-Hydrocortisone-Pramoxine 2.5% 1% Cream 1 Oz By Perrigo Pharma Only Physician, Pharmacy Or Licensed Facility Can purchase this RX Item Brand/Generic: , Drug Category: Anorectal PreparationsDrug Class: 84060800 Corticosteroids (Skin Mucous Membrane)
84080000 Antipruritics And Local Anesthetic

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PROCTOFOAM HC- hydrocortisone acetate and pramoxine hydrochloride aerosol, foam
Alaven Pharmaceutical LLC


topical aerosol

Rx Only

CIA71190BRev. 05/12

DESCRIPTION: Proctofoam� -HC (hydrocortisone acetate 1% and pramoxine hydrochloride 1%) is a topical aerosol foam for anal use containing hydrocortisone acetate 1% and pramoxine hydrochloride 1% in a hydrophilic base containing cetyl alcohol, emulsifying wax, methylparaben, polyoxyethylene-10-stearyl ether, propylene glycol, propylparaben, purified water, trolamine and inert propellants: isobutane and propane.



Proctofoam� -HC contains a synthetic corticosteroid used as an anti-inflammatory/antipruritic agent and a local anesthetic.

Hydrocortisone acetate
Molecular weight: 404.50. Solubility of hydrocortisone acetate in water: 1 mg/100 mL.

Chemical name: pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11?)-.

Chemical Structure
(click image for full-size original)
Pramoxine hydrochloride
Molecular weight: 329.86. Pramoxine hydrochloride is freely soluble in water.

Chemical name: morpholine, 4-[3-(4-butoxyphenoxy) propyl]-, hydrochloride.

Chemical Structure
(click image for full-size original)
CLINICAL PHARMACOLOGY:

Topical corticosteroids share anti-inflammatory, antipruritic and vasoconstrictive actions.

The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.

Pramoxine hydrochloride is a surface or local anesthetic which is not chemically related to the "caine" types of local anesthetics. Its unique chemical structure is likely to minimize the danger of cross-sensitivity reactions in patients allergic to other local anesthetics.

Pharmacokinetics: The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.

Topical corticosteroids can be absorbed through normal intact skin. Inflammation and/or other disease processes in the skin increase the percutaneous absorption of topical corticosteroids. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses. (See DOSAGE AND ADMINISTRATION.)

Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.

INDICATIONS AND USAGE:

Proctofoam� -HC is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses of the anal region.

Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649
RX ITEM-Hydrocortisone-Pramoxine 2.5% 1%
Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649

Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649
Hydrocortisone-Pramoxine 2.5% 1% Cream 1
Item No.:RX078477/H, Item No. RX078477, 078477, NDC No.: 45802-0472-64, 45802-472-64, 4580247264, 45802047264, 0472-64, 047264 UPC No. 3-45802-47264-9, 345802-472649, 345802472649

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
HYDROCORTISONE/PRAMOXINE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.