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Rx Item-Hydrocortisone Valerate 0.2% Cream 45Gm By Perrigo Pharma

NDC 45802-0455-42 UPC/GTIN No.3-45802-45542-0 Mfg.Part No.45542BRAND: HYDROCORT VALERATE NDC: 45802-0455-42,45802045542 UPC: 3-45802-45542-0,345802455420 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Hydrocortisone Valerate 0.2% Cream 45Gm By Perrigo Pharma

$86.64$99.02

Item No.:RX736009 NDC No.45802045542 UPC No.:345802455420 NDC No. 45802-0455-42 UPC/GTIN No. 3-45802-45542-0 MPN 45542 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx736009 Hydrocortisone Valerate 0.2% Cream 45gm by Perrigo Pharma Item No. 3736009 NDC No. 45802045542 UPC No. 345802455420 Other N

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HYDROCORTISONE VALERATE- hydrocortisone valerate cream
Perrigo New York Inc

For Dermatologic Use Only

Not For Ophthalmic Use

Rx Only

DESCRIPTION

Hydrocortisone Valerate Cream USP, 0.2% contains hydrocortisone valerate, 11,21-dihydroxy-17-[(1-oxopentyl)oxy]-(11?)-pregn-4-ene-3,20-dione, a synthetic corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and antipruritic agents.



Chemically, hydrocortisone valerate is C26 H38 O6 . It has the following structural formula:

Chemical Structure image
(click image for full-size original)
Hydrocortisone valerate has a molecular weight of 446.58. It is a white, crystalline solid, soluble in ethanol and methanol, sparingly soluble in propylene glycol and insoluble in water.

Each gram of Hydrocortisone Valerate Cream USP, 0.2% contains 2mg hydrocortisone valerate in a hydrophilic base composed of amphoteric-9, carbomer homopolymer type C, dibasic sodium phosphate, propylene glycol, purified water, sodium lauryl sulfate, sorbic acid, stearyl alcohol, and white petrolatum.

CLINICAL PHARMACOLOGY

Like other topical corticosteroids, hydrocortisone valerate has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2 .

Pharmacokinetics -
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier. Occlusive dressings with hydrocortisone for up to 24 hours have not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption.

Studies performed with Hydrocortisone Valerate Cream USP, 0.2% indicate that it is in the medium range of potency as compared with other topical corticosteroids.

INDICATIONS AND USAGE

Hydrocortisone Valerate Cream USP, 0.2% is a medium potency corticosteroid indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses in adult patients.

NDC 45802-0455-42 UPC/GTIN No.3-45802-45542-0 Mfg.Part No.45542
RX ITEM-Hydrocortisone Valerate 0.2% Cre
NDC 45802-0455-42 UPC/GTIN No.3-45802-45542-0 Mfg.Part No.45542

BRAND: HYDROCORT VALERATE NDC: 45802-0455-42,45802045542 UPC: 3-45802-45542-0,345802455420
Hydrocortisone Valerate 0.2% Cream 45Gm
BRAND: HYDROCORT VALERATE NDC: 45802-0455-42,45802045542 UPC: 3-45802-45542-0,345802455420

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
HYDROCORTISONE VALERATE T
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.