Rx Item-Hespan Iv 6% 0.9% Bag 12X500Ml By B.Braun

HESPAN- hetastarch and sodium chloride injection, solution
B. Braun Medical Inc.


WARNING: MORTALITY
RENAL REPLACEMENT THERAPY

In critically ill adult patients, including patients with sepsis, use of hydroxyethyl starch (HES) products, including HESPAN�, increases risk of
Mortality
Renal replacement therapy
Do not use HES products, including HESPAN�, in critically ill adult patients including patients with sepsis
1 INDICATIONS AND USAGE



HESPAN� is indicated in the treatment of hypovolemia when plasma volume expansion is desired. It is not a substitute for blood or plasma.

The adjunctive use of HESPAN� in leukapheresis has also been shown to be safe and efficacious in improving the harvesting and increasing the yield of granulocytes by centrifugal means.

2 DOSAGE AND ADMINISTRATION

Dosage for Acute Use in Plasma Volume Expansion

HESPAN� is administered by intravenous infusion only. Total dosage and rate of infusion depend upon the amount of blood or plasma lost and the resultant hemoconcentration.

2.1 Adults
The amount usually administered is 500 to 1000 mL. Doses of more than 1500 mL per day for the typical 70 kg patient (approximately 20 mL per kg of body weight) are usually not required. Higher doses have been reported in postoperative and trauma patients where severe blood loss has occurred [see Warnings and Precautions (5)].

2.2 Leukapheresis
250 to 700 mL of HESPAN� (6% hetastarch in 0.9% sodium chloride injection) with citrate anticoagulant is administered by aseptic addition to the input line of the centrifugation apparatus at a ratio of 1:8 to 1:13 to venous whole blood. The HESPAN� and citrate should be thoroughly mixed to assure effective anticoagulation of blood as it flows through the leukapheresis machine

RX ITEM-Hespan Iv 6% 0.9% Bag 12X500Ml B
NDC 00264-1965-10 UPC/GTIN No.3-02641-96510-2 Mfg.Part No.00264-1965-10

Hespan Iv 6% 0.9% Bag 12X500Ml By B.Brau
BRAND: HESPAN IV NDC: 00264-1965-10,264196510 UPC: 3-02641-96510-2,302641965102 B.Braun

HETASTARCH IN 0.9 % NACL
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