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Rx Item-Guanfacine 2Mg Tab 100 By Mylan Pharma

NDC 00378-1190-01 UPC/GTIN No.3-03781-19001-5 Mfg.Part No.119001BRAND: GUANFACINE NDC: 00378-1190-01,378119001 UPC: 3-03781-19001-5,303781190015 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Guanfacine 2Mg Tab 100 By Mylan Pharma

$117.60$125.66

Item No.:RX614990 NDC No.378119001 UPC No.:303781190015 NDC No. 00378-1190-01 UPC/GTIN No. 3-03781-19001-5 MPN 119001 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx614990 Guanfacine 2mg Tab 100 by Mylan Pharma Item No. 3614990 NDC No. 00378119001 UPC No. 303781190015 Other Name Tenex,Guanfa

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TENEX � guanfacine hydrochloride tablet
Promius Pharma, LLC
structurelabelTenex1mg

Tenex (guanfacine hydrochloride) is a centrally acting antihypertensive with ?2 -adrenoceptor agonist properties in tablet form for oral administration.

The chemical name of Tenex (guanfacine hydrochloride) is N-amidino- 2-(2,6-dichlorophenyl) acetamide hydrochloride and its molecular weight is 282.56
Guanfacine hydrochloride is a white to off-white powder; sparingly soluble in water and alcohol and slightly soluble in acetone. The tablets contain the following inactive ingredients:

1 mg�FD&C Red 40 aluminum lake, lactose, microcrystalline cellulose, povidone, stearic acid.

2 mg�D&C Yellow 10 aluminum lake, lactose, microcrystalline cellulose, povidone, stearic acid.
CLINICAL PHARMACOLOGY

Tenex (guanfacine hydrochloride) is an orally active antihypertensive agent whose principal mechanism of action appears to be stimulation of central ?2 -adrenergic receptors. By stimulating these receptors, guanfacine reduces sympathetic nerve impulses from the vasomotor center to the heart and blood vessels. This results in a decrease in peripheral vascular resistance and a reduction in heart rate.
INDICATIONS AND USAGE

Tenex (guanfacine hydrochloride) is indicated in the management of hypertension. Tenex may be given alone or in combination with other antihypertensive agents, especially thiazide-type diuretics.
CONTRAINDICATIONS

Tenex is contraindicated in patients with known hypersensitivity to guanfacine hydrochloride.
PRECAUTIONS
General

Like other antihypertensive agents, Tenex (guanfacine hydrochloride) should be used with caution in patients with severe coronary insufficiency, recent myocardial infarction, cerebrovascular disease, or chronic renal or hepatic failure.
Sedation

Tenex, like other orally active central ?2 -adrenergic agonists, causes sedation or drowsiness, especially when beginning therapy. These symptoms are dose-related (see ADVERSE REACTIONS). When Tenex is used with other centrally active depressants (such as phenothiazines, barbiturates, or benzodiazepines), the potential for additive sedative effects should be considered.
Rebound

Abrupt cessation of therapy with orally active central ?2 -adrenergic agonists may be associated with increases (from depressed on-therapy levels) in plasma and urinary catecholamines, symptoms of �nervousness and anxiety" and, less commonly, increases in blood pressure to levels significantly greater than those prior to therapy.
DOSAGE AND ADMINISTRATION

The recommended initial dose of Tenex (guanfacine hydrochloride) when given alone or in combination with another antihypertensive drug is 1 mg daily given at bedtime to minimize somnolence. If after 3 to 4 weeks of therapy 1 mg does not give a satisfactory result, a dose of 2 mg may be given, although most of the effect of Tenex is seen at 1 mg (see CLINICAL PHARMACOLOGY). Higher daily doses have been used, but adverse reactions increase significantly with doses above 3 mg/day.

The frequency of rebound hypertension is low, but it can occur. When rebound occurs, it does so after 2 � 4 days, which is delayed compared with clonidine hydrochloride. This is consistent with the longer half-life of guanfacine. In most cases, after abrupt withdrawal of guanfacine, blood pressure returns to pretreatment levels slowly (within 2 � 4 days) without ill effects.

NDC 00378-1190-01 UPC/GTIN No.3-03781-19001-5 Mfg.Part No.119001
RX ITEM-Guanfacine 2Mg Tab 100 By Mylan
NDC 00378-1190-01 UPC/GTIN No.3-03781-19001-5 Mfg.Part No.119001

BRAND: GUANFACINE NDC: 00378-1190-01,378119001 UPC: 3-03781-19001-5,303781190015
Guanfacine 2Mg Tab 100 By Mylan Pharma
BRAND: GUANFACINE NDC: 00378-1190-01,378119001 UPC: 3-03781-19001-5,303781190015

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.