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Rx Item-Glycopyrrolate 0.2Mg/Ml Vial 25X1Ml By American Regent Lab

NDC 00517-4601-25 UPC/GTIN No.3-05174-60125-2 Mfg.Part No.460125BRAND: GLYCOPYROLATE NDC: 00517-4601-25,517460125 UPC: 3-05174-60125-2,305174601252 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Glycopyrrolate 0.2Mg/Ml Vial 25X1Ml By American Regent Lab

$406.25$371.43

Item No.:RX557835 NDC No.517460125 UPC No.:305174601252 NDC No. 00517-4601-25 UPC/GTIN No. 3-05174-60125-2 MPN 460125 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx557835 Glycopyrrolate 0.2mg/ml Vial 25X1ml by American Regent Lab Item No. 3557835 NDC No. 00517460125 UPC No. 305174601252 Oth

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ROBINUL- glycopyrrolate injection
West-ward Pharmaceutical Corp.


Rx only
NOT FOR USE IN NEONATES
CONTAINS BENZYL ALCOHOL

DESCRIPTION

ROBINUL (glycopyrrolate) Injection is a synthetic anticholinergic agent. Each 1 mL contains:



Glycopyrrolate, USP 0.2 mg
Water for Injection, USP q.s.
Benzyl Alcohol, NF 0.9% (preservative)
pH adjusted, when necessary, with hydrochloric acid and/or sodium hydroxide.

For Intramuscular (IM) or Intravenous (IV) administration.

Glycopyrrolate is a quaternary ammonium salt with the following chemical name: 3[(cyclopentylhydroxyphenylacetyl)oxy]-1,1-dimethyl pyrrolidinium bromide. The molecular formula is C19 H28 BrNO3 and the molecular weight is 398.33.
C19 H28 BrNO3 MW 398.33Glycopyrrolate occurs as a white, odorless crystalline powder. It is soluble in water and alcohol, and practically insoluble in chloroform and ether.

Unlike atropine, glycopyrrolate is completely ionized at physiological pH values. ROBINUL (glycopyrrolate) Injection is a clear, colorless, sterile liquid; pH 2.0� 3.0. The partition coefficient of glycopyrrolate in a n-octanol/water system is 0.304 (log10 P= -1.52) at ambient room temperature (24�C).

CLINICAL PHARMACOLOGY

Glycopyrrolate, like other anticholinergic (antimuscarinic) agents, inhibits the action of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of smooth muscle, cardiac muscle, the sinoatrial node, the atrioventricular node, exocrine glands and, to a limited degree, in the autonomic ganglia. Thus, it diminishes the volume and free acidity of gastric secretions and controls excessive pharyngeal, tracheal, and bronchial secretions.

Glycopyrrolate antagonizes muscarinic symptoms (e.g., bronchorrhea, bronchospasm, bradycardia, and intestinal hypermotility) induced by cholinergic drugs such as the anticholinesterases.
INDICATIONS AND USAGE
Glycopyrrolate tablets 1 mg.

The recommended initial dosage of glycopyrrolate tablets 1 mg for adults is one tablet three times daily (in the morning, early afternoon, and at bedtime). Some patients may require two tablets at bedtime to assure overnight control of symptoms. For maintenance, a dosage of one tablet twice a day is frequently adequate.

Glycopyrrolate tablets 2 mg.

The recommended dosage of glycopyrrolate tablets 2 mg for adults is one tablet two or three times daily at equally spaced intervals.

Glycopyrrolate tablets are not recommended for use in pediatric patients under the age of 12 years

In Anesthesia
ROBINUL Injection is indicated for use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions; to reduce the volume and free acidity of gastric secretions; and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. When indicated, ROBINUL Injection may be used intraoperatively to counteract surgically or drug-induced or vagal reflexes associated arrhythmias. Glycopyrrolate protects against the peripheral muscarinic effects (e.g., bradycardia and excessive secretions) of cholinergic agents such as neostigmine and pyridostigmine given to reverse the neuromuscular blockade due to non-depolarizing muscle relaxants.

In Peptic Ulcer
For use in adults as adjunctive therapy for the treatment of peptic ulcer when rapid anticholinergic effect is desired or when oral medication is not tolerated.

NDC 00517-4601-25 UPC/GTIN No.3-05174-60125-2 Mfg.Part No.460125
RX ITEM-Glycopyrrolate 0.2Mg/Ml Vial 25X
NDC 00517-4601-25 UPC/GTIN No.3-05174-60125-2 Mfg.Part No.460125

BRAND: GLYCOPYROLATE NDC: 00517-4601-25,517460125 UPC: 3-05174-60125-2,305174601252
Glycopyrrolate 0.2Mg/Ml Vial 25X1Ml By A
BRAND: GLYCOPYROLATE NDC: 00517-4601-25,517460125 UPC: 3-05174-60125-2,305174601252

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
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Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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