Please email us at [email protected] with our item No, NDC#, UPC# or the product link if you have any quetions. We are located in Oceanside, California. Search over 110,000 items by Name, Item No., NDC, UPC (without dashes) or by Mfg.Name. Please note, Prescription items can only be ordered by a Drug Manufacturer, Wholesaler, Hospital, Governmental Medical Facility, VA, Pharmacy, Physician, Physician Assistant, Nurse Practitioner, Dentist, Podiatrist, Optometrist, Veterinarian, Naturopath, Licensed Lab, Physical Therapist & Pharmacist in their scope of practice. No order will ship, unless you you have provided us the Medical License (and DEA Lic. in case of controlled drug) and we had verified that. Rx items can only be shipped to AZ, AR, CA, CT, DE, FL, GA, GU, HI, IL, KS, KY, LA, ME, MA, MI, NJ, NY, PA, PR, TX, TN, VA, WA, WI and WV. If you are an International Physician or Pharmacist, please contact us before ordering.


Menu

Rx Item-Gadopentetate 5Ml By Alvogen Pharma

NDC 47781-0147-20 UPC/GTIN No.3-47781-14720-1 Mfg.Part No.14720BRAND: GADOPENTETATE NDC: 47781-0147-20,47781014720 UPC: 3-47781-14720-1,347781147201 Alvogen Inc.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Gadopentetate 5Ml By Alvogen Pharma

$0.00$512.65

Item No.:RX372896 NDC No.47781014720 UPC No.:347781147201 NDC No. 47781-0147-20 UPC/GTIN No. 3-47781-14720-1 MPN 14720 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx372896 Gadopentetate 5ml by Alvogen Pharma Item No. 3372896 NDC No. 47781014720 UPC No. 347781147201 Other Name Gadavist,Gadopente

Have a question?

GADOPENTETATE DIMEGLUMINE- gadopentetate dimeglumine injection
Alvogen, Inc

WARNING: NEPHROGENIC SYSTEMIC FIBROSIS (NSF)

Gadolinium-based contrast agents (GBCAs) increase the risk for NSF among patients with

impaired elimination of the drugs. Avoid use of GBCAs in these patients unless the diagnostic

information is essential and not available with non-contrasted MRI or other modalities. NSF may

result in fatal or debilitating fibrosis affecting the skin, muscle and internal organs.

� Do not administer gadopentetate dimeglumine to patients with:



? chronic, severe kidney disease (GFR < 30 mL/min/1.73m2), or

? acute kidney injury (see CONTRAINDICATIONS).

� Screen patients for acute kidney injury and other conditions that may reduce renal function.

For patients at risk for chronically reduced renal function (for example, age >60 years,

hypertension or diabetes), estimate the glomerular filtration rate (GFR) through laboratory

testing.

Do not exceed the recommended gadopentetate dimeglumine dose and allow a sufficient period

of time for elimination of the drug from the body prior to any re-administration (see WARNINGS

AND PRECAUTIONS).

DESCRIPTION

Gadopentetate dimeglumine Injection is the N-methylglucamine salt of the gadolinium complex of diethylenetriamine pentaacetic acid, and is an injectable contrast medium for magnetic resonance imaging (MRI). Gadopentetate dimeglumine Injection is provided as a sterile, clear, colorless to slightly yellow aqueous solution for intravenous injection.

Gadopentetate dimeglumine Injection is a 0.5-mol/L solution of 1-deoxy-1-(methylamino)-D-glucitol dihydrogen [N,N-bis[2-[bis(carboxymethyl)amino]ethyl] glycinato(5-)]gadolinate(2-)(2:1) with a molecular weight of 938, an empirical formula of C28 H54 GdN5 O20 , and has the following structural formula:

Chemical Structure
(click image for full-size original)
Each mL contains 469.01 mg gadopentetate dimeglumine, 0.99 mg meglumine, 0.40 mg diethylenetriamine pentaacetic acid and water for injection. Gadopentetate dimeglumine Injection contains no antimicrobial preservative.

Gadopentetate dimeglumine Injection has a pH of 6.5 to 8.0. Pertinent physicochemical data are noted below:

PARAMETER

Osmolality (mOsmol/kg water)

at 37� C

1,960

Viscosity (CP)

at 20� C

4.9

at 37� C

2.9

Density (g/mL)

at 25� C

1.195

Specific Gravity

at 25� C

1.208

Octanol: H2 O Coefficient

at 25� C, pH7 log Pow = � 5.4

Gadopentetate dimeglumine Injection has an osmolality 6.9 times that of plasma which has an osmolality of 285 mOsmol/kg water. Gadopentetate dimeglumine Injection is hypertonic under conditions of use.

CLINICAL PHARMACOLOGY

Pharmacokinetics
The pharmacokinetics of intravenously administered gadopentetate dimeglumine in normal subjects conforms to a two compartment open-model with mean distribution and elimination half-lives (reported as mean � SD) of about 0.2 � 0.13 hours and 1.6 � 0.13 hours, respectively.

Upon injection, the meglumine salt is completely dissociated from the gadopentetate dimeglumine complex. Gadopentetate is exclusively eliminated in the urine with 83 � 14% (mean � SD) of the dose excreted within 6 hours and 91 � 13% (mean � SD) by 24 hours, post-injection. There was no detectable biotransformation or decomposition of gadopentetate dimeglumine.

The renal and plasma clearance rates (1.76 � 0.39 mL/min/kg and 1.94 � 0.28 mL/min/kg, respectively) of gadopentetate are essentially identical, indicating no alteration in elimination kinetics on passage through the kidneys and that the drug is essentially cleared through the kidney. The volume of distribution (266 � 43 mL/kg) is equal to that of extracellular water and clearance is similar to that of substances which are subject to glomerular filtration.

In vitro laboratory results indicate that gadopentetate does not bind to human plasma protein. In vivo protein binding studies have not been done.

NDC 47781-0147-20 UPC/GTIN No.3-47781-14720-1 Mfg.Part No.14720
RX ITEM-Gadopentetate 5Ml By Alvogen Pha
NDC 47781-0147-20 UPC/GTIN No.3-47781-14720-1 Mfg.Part No.14720

BRAND: GADOPENTETATE NDC: 47781-0147-20,47781014720 UPC: 3-47781-14720-1,347781147201 Alvogen Inc.
Gadopentetate 5Ml By Alvogen Pharma
BRAND: GADOPENTETATE NDC: 47781-0147-20,47781014720 UPC: 3-47781-14720-1,347781147201 Alvogen Inc.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
AmericanPharmaWholesale.com
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
Buy More Save More!
Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.