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Rx Item-Estradiol Valerate 40Mg/Ml Vial 5Ml By Perrigo Pharma(Delestrogen)

NDC 00574-0872-05 UPC/GTIN No.3-05740-87205-5 Mfg.Part No.87205  Brand Name	DELESTROGEN 40MG/ML Rx item
Generic Name	ESTRADIOL VALERATE 40MG/ML
Product Description	MDV (IJ)
NDC Code	00574087205
MaBRAND: ESTRADIOL NDC: 00574-0872-05,574087205 UPC: 3-05740-87205-5,305740872055 Perrigo Co Estradiol Valerate 40mg/ml Vial 5ml by Perrigo Pharma(Delestrogen)Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Estradiol Valerate 40Mg/Ml Vial 5Ml By Perrigo Pharma(Delestrogen)

$239.38$273.58

Item No.:RX096131/a, Item No. RX096131, 096131, NDC No.: 00574-0872-05, 00574-872-05, 0057487205, 00574087205, 0872-05, 087205 UPC No. 3-05740-87205-5, 305740-872055, 305740872055, Rx Item-Estradiol Valerate 40Mg/Ml Vial 5Ml By Perrigo Pharma(Delestrogen) Only Physician, Pharmacy Or Licensed Facility Can purchase this RX Item Brand/Generic: , Drug Category: Hormones Supplements-EstrogensDrug Class: 68160400 Estrogens

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ESTRADIOL VALERATE- estradiol valerate injection, solution
Perrigo Company


ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER
Close clinical surveillance of all women taking estrogens is important. Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. There is no evidence that the use of "natural" estrogens results in a different endometrial risk profile than synthetic estrogens at equivalent estrogen doses. (See WARNINGS, Malignant neoplasms, Endometrial cancer.)

CARDIOVASCULAR AND OTHER RISKS


Estrogens and progestins should not be used for the prevention of cardiovascular disease. (See WARNINGS, Cardiovascular disorders.)

The Women's Health Initiative (WHI) study reported increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) during 5 years of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone acetate (MPA 2.5 mg) relative to placebo. (See CLINICAL PHARMACOLOGY, Clinical Studies. )

The Women's Health Initiative Memory Study (WHIMS), a substudy of WHI, reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 4 years of treatment with oral conjugated estrogens plus medroxyprogesterone acetate relative to placebo. It is unknown whether this finding applies to younger postmenopausal women or to women taking estrogen alone therapy. (See CLINICAL PHARMACOLOGY, Clinical Studies.)

Other doses of oral conjugated estrogens with medroxyprogesterone acetate, and other combinations and dosage forms of estrogens and progestins were not studied in the WHI clinical trials and, in the absence of comparable data, these risks should be assumed to be similar. Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.

DESCRIPTION

Estradiol Valerate Injection, USP contains estradiol valerate, a long-acting estrogen in sterile oil solutions for intramuscular use. These solutions are clear, colorless to pale yellow. Formulations (per mL): 20 mg estradiol valerate in a vehicle containing 224 mg benzyl benzoate, 20 mg benzyl alcohol (preservative), and castor oil; 40 mg estradiol valerate in a vehicle containing 447 mg benzyl benzoate, 20 mg benzyl alcohol, and castor oil.

Estradiol valerate is designated chemically as estra-1,3,5(10) � triene-3, 17 � diol(17 ?) - , 17-pentanoate.

Graphic formula:

Chemical Structure
(click image for full-size original)
C23 H32 O3 MW 356.50

CLINICAL PHARMACOLOGY

Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol, at the receptor level.

NDC 00574-0872-05 UPC/GTIN No.3-05740-87205-5 Mfg.Part No.87205  Brand Name	DELESTROGEN 40MG/ML Rx item
Generic Name	ESTRADIOL VALERATE 40MG/ML
Product Description	MDV (IJ)
NDC Code	00574087205
Ma
RX ITEM-Estradiol Valerate 40Mg/Ml Vial
NDC 00574-0872-05 UPC/GTIN No.3-05740-87205-5 Mfg.Part No.87205 Brand Name DELESTROGEN 40MG/ML Rx item Generic Name ESTRADIOL VALERATE 40MG/ML Product Description MDV (IJ) NDC Code 00574087205 Ma

BRAND: ESTRADIOL NDC: 00574-0872-05,574087205 UPC: 3-05740-87205-5,305740872055 Perrigo Co Estradiol Valerate 40mg/ml Vial 5ml by Perrigo Pharma(Delestrogen)
Estradiol Valerate 40Mg/Ml Vial 5Ml By P
BRAND: ESTRADIOL NDC: 00574-0872-05,574087205 UPC: 3-05740-87205-5,305740872055 Perrigo Co Estradiol Valerate 40mg/ml Vial 5ml by Perrigo Pharma(Delestrogen)

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
ESTRADIOL VALERATE INTRAM
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.