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Rx Item-Dopamine-Dextrose 800Mg .25L Bag 12X250Ml By Hospira Worldwide

NDC 00409-7810-22 UPC/GTIN No.3-04097-81022-2 Mfg.Part No.781022BRAND: DOPAMINE-DEXTROSE NDC: 00409-7810-22,409781022 UPC: 3-04097-81022-2,304097810222 Hospira Worldwide Inc.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Dopamine-Dextrose 800Mg .25L Bag 12X250Ml By Hospira Worldwide

$279.60$264.94

Item No.:RX162198 NDC No.409781022 UPC No.:304097810222 NDC No. 00409-7810-22 UPC/GTIN No. 3-04097-81022-2 MPN 781022 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx162198 Dopamine-Dextrose 800mg/.25L Bag 12X250ml by Hospira Worldwide Item No. 3162198 NDC No. 00409781022 UPC No. 304097810222

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DOPAMINE HYDROCHLORIDE- dopamine hydrochloride injection, solution, concentrate
Hospira, Inc.

Injection, USP

Fliptop Vial Pintop Vial

MUST BE DILUTED PRIOR TO ADMINISTRATION

DESCRIPTION

Dopamine, a sympathomimetic amine vasopressor, is the naturally occurring immediate precursor of norepinephrine. Dopamine hydrochloride is a white to off-white crystalline powder, which may have a slight odor of hydrochloric acid. It is freely soluble in water and soluble in alcohol. Dopamine HCl is sensitive to alkalies, iron salts, and oxidizing agents. Chemically it is designated as 4-(2-aminoethyl) pyrocatechol hydrochloride, and its molecular formula is C8 H11 NO2 � HCl.



The structural formula is:

structural formula dopamine
(click image for full-size original)
and the molecular weight is 189.64.

Dopamine hydrochloride injection is a clear, practically colorless, sterile, pyrogen-free, aqueous solution of dopamine HCl for intravenous infusion after dilution. Each milliliter of the 40 mg/mL preparation contains 40 mg of dopamine hydrochloride (equivalent to 32.31 mg of dopamine base). Each milliliter of the 80 mg/mL preparation contains 80 mg of dopamine hydrochloride (equivalent to 64.62 mg of dopamine base). Each milliliter of both preparations contains the following: Sodium metabisulfite 9 mg added as an antioxidant; citric acid, anhydrous 10 mg; and sodium citrate, dihydrate 5 mg added as a buffer. May contain additional citric acid and/or sodium citrate for pH adjustment. pH is 3.3 (2.5 to 5.0).

Dopamine must be diluted in an appropriate sterile parenteral solution before intravenous administration. (See DOSAGE AND ADMINISTRATION)

CLINICAL PHARMACOLOGY

Dopamine is a natural catecholamine formed by the decarboxylation of 3,4-dihydroxyphenylalanine (DOPA). It is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system, especially in the nigrostriatal tract, and in a few peripheral sympathetic nerves.

Dopamine produces positive chronotropic and inotropic effects on the myocardium, resulting in increased heart rate and cardiac contractility. This is accomplished directly by exerting an agonist action on beta-adrenoceptors and indirectly by causing release of norepinephrine from storage sites in sympathetic nerve endings.

Dopamine�s onset of action occurs within five minutes of intravenous administration, and with dopamine�s plasma half-life of about two minutes, the duration of action is less than ten minutes. However, if monoamine oxidase (MAO) inhibitors are present, the duration may increase to one hour. The drug is widely distributed in the body but does not cross the blood-brain barrier to a significant extent. Dopamine is metabolized in the liver, kidney, and plasma by MAO and catechol-O-methyltransferase to the inactive compounds homovanillic acid (HVA) and 3,4-dihydroxyphenylacetic acid. About 25% of the dose is taken up into specialized neurosecretory vesicles (the adrenergic nerve terminals), where it is hydroxylated to form norepinephrine. It has been reported that about 80% of the drug is excreted in the urine within 24 hours, primarily as HVA and its sulfate and glucuronide conjugates and as 3,4-dihydroxyphenylacetic acid. A very small portion is excreted unchanged.

NDC 00409-7810-22 UPC/GTIN No.3-04097-81022-2 Mfg.Part No.781022
RX ITEM-Dopamine-Dextrose 800Mg .25L Bag
NDC 00409-7810-22 UPC/GTIN No.3-04097-81022-2 Mfg.Part No.781022

BRAND: DOPAMINE-DEXTROSE NDC: 00409-7810-22,409781022 UPC: 3-04097-81022-2,304097810222 Hospira Worldwide Inc.
Dopamine-Dextrose 800Mg .25L Bag 12X250M
BRAND: DOPAMINE-DEXTROSE NDC: 00409-7810-22,409781022 UPC: 3-04097-81022-2,304097810222 Hospira Worldwide Inc.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
DOPAMINE HCL/D5W INTRAVEN
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.