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Rx Item-Desowen 0.05% Lotion 4 Oz By Galderma Labs

NDC 00299-5765-04 UPC/GTIN No.3-02995-76504-9 Mfg.Part No.576504BRAND: DESOWEN NDC: 00299-5765-04,299576504 UPC: 3-02995-76504-9,302995765049 Galderma Labs Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Desowen 0.05% Lotion 4 Oz By Galderma Labs

$718.20$684.00

Item No.:RX542944 NDC No.299576504 UPC No.:302995765049 NDC No. 00299-5765-04 UPC/GTIN No. 3-02995-76504-9 MPN 576504 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item. Rx Item No. Rx542944 Desowen 0.05% Lotion 4 oz by Galderma Labs, Item No. 3542944 NDC No. 00299576504 UPC No. 302995765049 Other Name Desonat

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DESONIDE- desonide cream
DESONIDE- desonide lotion
Actavis Pharma, Inc.


DESCRIPTION:

Desonide Cream 0.05% and Lotion 0.05% contain desonide (Pregna-1,4-diene-3,20-dione,11,21-dihydroxy-16,17 [(1-methylethylidene)bis(oxy)]-,(11?,16?)- a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as anti-inflammatory and anti-pruritic agents.

Chemically, desonide is C24 H32 O6 . It has the following structural formula:

desowen-structure-01


Desonide has the molecular weight of 416.51. It is a white to off white odorless powder which is soluble in methanol and practically insoluble in water.

Each gram of Desonide Cream contains 0.5 mg of desonide in a base of citric acid, emulsifying wax, isopropyl palmitate, polysorbate 60, potassium sorbate, propyl gallate, propylene glycol, purified water, sodium hydroxide, sorbic acid, stearic acid, and synthetic beeswax.

Each gram of Desonide Lotion contains 0.5 mg of desonide in a base of cetyl alcohol, edetate sodium, glyceryl stearate SE, light mineral oil, methylparaben, propylene glycol, propylparaben, purified water, sodium lauryl sulfate, sorbitan monostearate, and stearyl alcohol. May contain citric acid and/or sodium hydroxide for pH adjustment.

CLINICAL PHARMACOLOGY:

Like other topical corticosteroids, desonide has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2 .

Pharmacokinetics:
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier. Occlusive dressings with hydrocortisone for up to 24 hours have not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin may increase percutaneous absorption.

Studies performed with Desonide Cream and Lotion indicate that they are in the low to medium range of potency as compared with other topical corticosteroids.

INDICATIONS AND USAGE:

Desonide Cream and Lotion are low to medium potency corticosteroids indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid responsive dermatoses.

NDC 00299-5765-04 UPC/GTIN No.3-02995-76504-9 Mfg.Part No.576504
RX ITEM-Desowen 0.05% Lotion 4 Oz By Gal
NDC 00299-5765-04 UPC/GTIN No.3-02995-76504-9 Mfg.Part No.576504

BRAND: DESOWEN NDC: 00299-5765-04,299576504 UPC: 3-02995-76504-9,302995765049 Galderma Labs
Desowen 0.05% Lotion 4 Oz By Galderma La
BRAND: DESOWEN NDC: 00299-5765-04,299576504 UPC: 3-02995-76504-9,302995765049 Galderma Labs

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
DESONIDE TOPICAL LOTION 0
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.