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Rx Item-Cromolyn Sodium 20Mg/2 Ml Amp 60X2Ml By Teva Pharma Gen Intal

NDC 00172-6406-49 UPC/GTIN No.3-01726-40649-8 Mfg.Part No.640649BRAND: CROMOLYN NDC: 00172-6406-49,172640649 UPC: 3-01726-40649-8,301726406498 Teva Pharmaceuticals USAOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Cromolyn Sodium 20Mg/2 Ml Amp 60X2Ml By Teva Pharma Gen Intal

$407.89$359.99

item No.:RX002477/a NDC No.172640649 UPC No.:301726406498 NDC No. 00172-6406-49 UPC/GTIN No. 3-01726-40649-8 MPN 640649 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX item. Rx Item No. Rx002477 Cromolyn Sodium 20mg/2 ml Amp 60X2ml by Teva Pharma Item No. 3002477 NDC No. 00172640649 UPC No. 301726406498 Other Name C

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CROMOLYN SODIUM- cromolyn sodium solution
Wallace Pharmaceuticals Inc.

DESCRIPTION: Each 5 mL ampule of Cromolyn Sodium, USP contains 100 mg Cromolyn Sodium, USP, in purified water. Cromolyn sodium is a hygroscopic, white powder having little odor. It may leave a slightly bitter aftertaste. Cromolyn Sodium, USP Oral Concentrate is clear, colorless, and sterile. It is intended for oral use.

Chemically, cromolyn sodium is disodium 5,5'-[(2-hydroxytrimethylene)dioxy]bis[4-oxo-4H-1-benzopyran-2-carboxylate]. The empirical formula is C23 H14 Na2 O11 ; the molecular weight is 512.34. Its chemical structure is:

Structural Formula


Pharmacologic Category: Mast cell stabilizer

Therapeutic Category: Antiallergic

CLINICAL PHARMACOLOGY: In vitro and in vivo animal studies have shown that cromolyn sodium inhibits the release of mediators from sensitized mast cells. Cromolyn sodium acts by inhibiting the release of histamine and leukotrienes (SRS-A) from the mast cell.

Cromolyn sodium has no intrinsic vasoconstrictor, antihistamine, or glucocorticoid activity.

Cromolyn sodium is poorly absorbed from the gastrointestinal tract. No more than 1% of an administered dose is absorbed by humans after oral administration, the remainder being excreted in the feces. Very little absorption of cromolyn sodium was seen after oral administration of 500 mg by mouth to each of 12 volunteers. From 0.28 to 0.50% of the administered dose was recovered in the first 24 hours of urinary excretion in 3 subjects. The mean urinary excretion of an administered dose over 24 hours in the remaining 9 subjects was 0.45%.

CLINICAL STUDIES: Four randomized, controlled clinical trials were conducted with Cromolyn Sodium, USP in patients with either cutaneous or systemic mastocytosis; two of which utilized a placebo-controlled crossover design, one utilized an active-controlled (chlorpheniramine plus cimetidine) crossover design, and one utilized a placebo-controlled parallel group design. Due to the rare nature of this disease, only 36 patients qualified for study entry, of whom 32 were considered evaluable. Consequently, formal statistical analyses were not performed. Clinically significant improvement in gastrointestinal symptoms (diarrhea, abdominal pain) were seen in the majority of patients with some improvement also seen for cutaneous manifestations (urticaria, pruritus, flushing) and cognitive function. The benefit seen with Cromolyn Sodium, USP 200 mg QID was similar to chlorpheniramine (4 mg QID) plus cimetidine (300 mg QID) for both cutaneous and systemic symptoms of mastocytosis.

Clinical improvement occurred within 2-6 weeks of treatment initiation and persisted for 2-3 weeks after treatment withdrawal. Cromolyn Sodium, USP did not affect urinary histamine levels or peripheral eosinophilia, although neither of these variables appeared to correlate with disease severity. Positive clinical benefits were also reported for 37 of 51 patients who received Cromolyn Sodium, USP in United States and foreign humanitarian programs.

INDICATIONS AND USAGE: Cromolyn Sodium, USP is indicated in the management of patients with mastocytosis. Use of this product has been associated with improvement in diarrhea, flushing, headaches, vomiting, urticaria, abdominal pain, nausea, and itching in some patients.

NDC 00172-6406-49 UPC/GTIN No.3-01726-40649-8 Mfg.Part No.640649
RX ITEM-Cromolyn Sodium 20Mg/2 Ml Amp 60
NDC 00172-6406-49 UPC/GTIN No.3-01726-40649-8 Mfg.Part No.640649

BRAND: CROMOLYN NDC: 00172-6406-49,172640649 UPC: 3-01726-40649-8,301726406498 Teva Pharmaceuticals USA
Cromolyn Sodium 20Mg/2 Ml Amp 60X2Ml By
BRAND: CROMOLYN NDC: 00172-6406-49,172640649 UPC: 3-01726-40649-8,301726406498 Teva Pharmaceuticals USA

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
CROMOLYN SODIUM INHALATIO
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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