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Rx Item-Cosopt PF Dorzolamide-Timolol 2% 0.5% Dpt 60x.2ml By Akorn Pharma

Item No.:RX334839 334839  NDC No.82584-0604-30 82584-604-30 82584060430 8258460430   UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430Item No.:RX334839 334839  NDC No.82584-0604-30 82584-604-30 82584060430 8258460430   UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Cosopt PF Dorzolamide-Timolol 2% 0.5% Dpt 60x.2ml By Akorn Pharma

$229.62$209.99

Item No.:RX750058 750058 NDC No.82584-0604-30 82584-604-30 82584060430 8258460430 UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,ResearchCo.,Uni.,VA,Vet & Wholesalers in scope of practice can order this RX Item.

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Clinical Information
Gen. Code and Des.
61877 dorzolamide/timolol/PF OPHTHALMIC DROPERETTE 2 %-0.5 %
GCN and Des.
97662 dorzolamide/timolol/PF OPHTHALMIC DROPERETTE 2 %-0.5 %
Strength
2-0.5%
Dose Form
DROPPERETTE, SINGLE-USE DROP DISPENSER
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
52401200 CARBONIC ANHYDRASE INHIBITORS (EENT)
52400800 BETA-ADRENERGIC BLOCKING AGENTS (EENT)
Active Ingredients
1856 timolol maleate 26921175
4999 dorzolamide HCl 130693822
9870 preservative free
Inactive Ingredients
2272 mannitol 69658
2332 sodium citrate 68042





COSOPT- dorzolamide hydrochloride and timolol maleate solution


DESCRIPTION

COSOPT� (dorzolamide hydrochloride-timolol maleate ophthalmic solution) is the combination of a topical carbonic anhydrase inhibitor and a topical beta-adrenergic receptor blocking agent.

Dorzolamide hydrochloride is described chemically as: (4S- trans)-4-(ethylamino)-5,6-dihydro-6-methyl-4H -thieno[2,3-b ]thiopyran-2-sulfonamide 7,7-dioxide monohydrochloride. Dorzolamide hydrochloride is optically active. The specific rotation is:



[?] 25�C (C=1, water) = ~ -17�.

405 nm

Its empirical formula is C10 H16 N2 O4 S3 �HCl and its structural formula is:

chemical structure for dorzolamide hydrochloride
Dorzolamide hydrochloride has a molecular weight of 360.91. It is a white to off-white, crystalline powder, which is soluble in water and slightly soluble in methanol and ethanol.

Timolol maleate is described chemically as: (-)-1-(tert -butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol maleate (1:1) (salt). Timolol maleate possesses an asymmetric carbon atom in its structure and is provided as the levo-isomer. The optical rotation of timolol maleate is:

[?] 25�C in 1N HCl (C = 5) = -12.2� (-11.7� to -12.5�).

405 nm

Its molecular formula is C13 H24 N4 O3 S�C4 H4 O4 and its structural formula is:

chemical structure for timolol maleate
(click image for full-size original)
Timolol maleate has a molecular weight of 432.50. It is a white, odorless, crystalline powder which is soluble in water, methanol, and alcohol. Timolol maleate is stable at room temperature.

COSOPT is supplied as a sterile, isotonic, buffered, slightly viscous, aqueous solution. The pH of the solution is approximately 5.65, and the osmolarity is 242-323 mOsM. Each mL of COSOPT contains 20 mg dorzolamide (22.26 mg of dorzolamide hydrochloride) and 5 mg timolol (6.83 mg timolol maleate). Inactive ingredients are sodium citrate, hydroxyethyl cellulose, sodium hydroxide, mannitol, and water for injection. Benzalkonium chloride 0.0075% is added as a preservative.

Item No.:RX334839 334839  NDC No.82584-0604-30 82584-604-30 82584060430 8258460430   UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430
Cosopt PF Dorzolamide-Timolol
Item No.:RX334839 334839 NDC No.82584-0604-30 82584-604-30 82584060430 8258460430 UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430

Item No.:RX334839 334839  NDC No.82584-0604-30 82584-604-30 82584060430 8258460430   UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430
Cosopt PF Dorzolamide-Timolol
Item No.:RX334839 334839 NDC No.82584-0604-30 82584-604-30 82584060430 8258460430 UPC/GTIN No. 382584-604301 3-82584-60430-1 382584604301 MPN 60430

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.