Rx Item-Combigan 0.2% 0.5% Drops 5Ml By Allergan Pharma

COMBIGAN- brimonidine tartrate and timolol maleate solution/ drops
Allergan, Inc.

1 INDICATIONS AND USAGE

COMBIGAN� (brimonidine tartrate/timolol maleate ophthalmic solution) 0.2%/0.5% is an alpha-adrenergic receptor agonist with a beta-adrenergic receptor inhibitor indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who require adjunctive or replacement therapy due to inadequately controlled IOP; the IOP-lowering of COMBIGAN� dosed twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol maleate ophthalmic solution dosed twice a day and 0.2% brimonidine tartrate ophthalmic solution dosed three times per day.

2 DOSAGE AND ADMINISTRATION



The recommended dose is one drop of COMBIGAN� in the affected eye(s) twice daily approximately 12 hours apart. If more than one topical ophthalmic product is to be used, the different products should be instilled at least 5 minutes apart.

3 DOSAGE FORMS AND STRENGTHS

Solution containing 2 mg/mL brimonidine tartrate and 5 mg/mL timolol (6.8 mg/mL timolol maleate).

RX ITEM-Combigan 0.2% 0.5% Drops 5Ml By
NDC 00023-9211-05 UPC/GTIN No.3-00239-21105-6 Mfg.Part No.921105

Combigan 0.2% 0.5% Drops 5Ml By Allergan
BRAND: COMBIGAN NDC: 00023-9211-05,23921105 UPC: 3-00239-21105-6,300239211056 Allergan USA, Inc.

BRIMONIDINE TARTRATE/TIMO
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