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Rx Item-Clotrimazole Powder(Non-Sterile Pharmaceutical Grade ) 100Gm By Me

NDC 38779-0019-05 UPC/GTIN No.0-38779-00195-9 Mfg.Part No.1905Medisca Inc.This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Clotrimazole Powder(Non-Sterile Pharmaceutical Grade ) 100Gm By Me

$877.80$89.35

Item No.:RX175471 NDC No. 38779-0019-05 UPC/GTIN No. 0-38779-00195-9 MPN 1905 Only Physician,Pharmacy or Licensed Facility can order this Rx Item No. Rx175471 Clotrimazole Powder (Non-Sterile Pharmaceutical Grade ) 100gm by Medisca Item No. 3175471 NDC No. 38779001905 UPC No. 038779001959 Other Name Lotrimin,Gyne-Lotrimin,Gyne Lotrimin, Mpm Anti-Fungal,Cruex Therapeutic Code 840408 Therapeutic Class Antifulgals(Skin & Mucous Membrane),Misc Item Class Non Controlled Rx. Case Qnty: 1 Therapeutic C

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CLOTRIMAZOLE- clotrimazole lozenge
Paddock Laboratories, LLC

FOR TOPICAL ORAL ADMINISTRATION

DESCRIPTION

Each clotrimazole lozenge contains 10 mg clotrimazole [1-(o-chloro-?, ?-diphenylbenzyl) imidazole], a synthetic antifungal agent, for topical use in the mouth.

Structural Formula:

Chemical Structure
Chemical Formula:



C22 H17 ClN2

The lozenge dosage form is a large, slowly dissolving tablet (troche) containing 10 mg of clotrimazole dispersed in dextrose, microcrystalline cellulose, povidone, and magnesium stearate.

CLINICAL PHARMACOLOGY

Clotrimazole is a broad-spectrum antifungal agent that inhibits the growth of pathogenic yeasts by altering the permeability of cell membranes. The action of clotrimazole is fungistatic at concentrations of drug up to 20 mcg/mL and may be fungicidal in vitro against Candida albicans and other species of the genus Candida at higher concentrations. No single-step or multiple-step resistance to clotrimazole has developed during successive passages of Candida albicans in the laboratory; however, individual organism tolerance has been observed during successive passages in the laboratory. Such in vitro tolerance has resolved once the organism has been removed from the antifungal environment.

After oral administration of a 10 mg clotrimazole lozenge to healthy volunteers, concentrations sufficient to inhibit most species of Candida persist in saliva for up to three hours following the approximately 30 minutes needed for a lozenge to dissolve. The long term persistence of drug in saliva appears to be related to the slow release of clotrimazole from the oral mucosa to which the drug is apparently bound. Repetitive dosing at three hour intervals maintains salivary levels above the minimum inhibitory concentrations of most strains of Candida; however, the relationship between in vitro susceptibility of pathogenic fungi to clotrimazole and prophylaxis or cure of infections in humans has not been established.

In another study, the mean serum concentrations were 4.98 � 3.7 and 3.23 � 1.4 nanograms/mL of clotrimazole at 30 and 60 minutes, respectively, after administration as a lozenge.

INDICATIONS AND USAGE

Clotrimazole lozenges are indicated for the local treatment of oropharyngeal candidiasis. The diagnoses should be confirmed by a KOH smear and/or culture prior to treatment.

Clotrimazole lozenges are also indicated prophylactically to reduce the incidence of oropharyngeal candidiasis in patients immunocompromised by conditions that include chemotherapy, radiotherapy, or steroid therapy utilized in the treatment of leukemia, solid tumors, or renal transplantation. There are no data from adequate and well-controlled trials to establish the safety and efficacy of this product for prophylactic use in patients immunocompromised by etiologies other than those listed in the previous sentence. (See DOSAGE AND ADMINISTRATION.)

NDC 38779-0019-05 UPC/GTIN No.0-38779-00195-9 Mfg.Part No.1905
Clotrimazole Pwd 100gm by Medisca
NDC 38779-0019-05 UPC/GTIN No.0-38779-00195-9 Mfg.Part No.1905

Medisca Inc.

Medisca Inc.

This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).
CLOTRIMAZOLE MISCELL POWD
This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.