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Rx Item-Chlorthalidone 25mg Tab 100 By Mylan Institutional

Item No.: RX114348 NDC No.51079005820 UPC No.:351079058202 NDC No. 51079-0058-20 UPC/GTIN No. 3-51079-05820-2 MPN No. 5820 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.LBRAND: CHLORTHALIDONE NDC: 51079-0058-20,51079005820 UPC: 3-51079-05820-2,351079058202 Mylan Institutional/PgnOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Chlorthalidone 25mg Tab 100 By Mylan Institutional

$229.53$178.57

Item No.: RX114348 NDC No.51079005820 UPC No.:351079058202 NDC No. 51079-0058-20 UPC/GTIN No. 3-51079-05820-2 MPN No. 5820 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order RX Item. RX Item No. RX114348 Chlorthalidone 25mg Tab 100 By Mylan Institutional/ Item No. 3114348 NDC No. 51079005820 UPC No. 3

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CHLORTHALIDONE- chlorthalidone tablet
PLIVA

Chlorthalidone is an oral antihypertensive/diuretic. It is a monosulfamyl diuretic that differs chemically from thiazide diuretics in that a double-ring system is incorporated in its structure. It is 2-chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl) benzenesulfonamide, with the following structural formula:

Image from Drug Label Content
C14 H11 CIN2 O4 S M.W. 338.76

Chlorthalidone is practically insoluble in water, in ether and in chloroform; soluble in methanol; slightly soluble in alcohol.



Each tablet for oral administration contains 25 mg or 50 mg of chlorthalidone, USP.

Tablets also contain colloidal silicon dioxide, crospovidone, anhydrous lactose, povidone, sodium starch glycolate, stearic acid, FD&C Yellow #6 (25 mg), FD&C Blue #1 (50 mg) and D&C Yellow #10 (50 mg).

CLINICAL PHARMACOLOGY

Chlorthalidone is an oral diuretic with prolonged action (48-72 hours) and low toxicity. The major portion of the drug is excreted unchanged by the kidneys. The diuretic effect of the drug occurs in approximately 2.6 hours and continues for up to 72 hours. The mean half-life following a 50 to 200 mg dose is 40 hours. In the first order of absorption, the elimination half-life is 53 hours following a 50 mg dose and 60 hours following a 100 mg dose. Approximately 75 percent of the drug is bound to plasma proteins, 58 percent of the drug being bound to albumin. This is caused by an increased affinity of the drug to erythrocyte carbonic anhydrase. Nonrenal routes of elimination have yet to be clarified. Data are not available regarding percentage of dose as unchanged drug and metabolites, concentration of the drug in body fluids, degree of uptake by a particular organ or in the fetus, or passage across the blood-brain barrier.

The drug produces copious diuresis with greatly increased excretion of sodium and chloride. At maximal therapeutic dosage chlorthalidone is approximately equal in its diuretic effect to comparable maximal therapeutic doses of benzothiadiazine diuretics. The site of action appears to be the cortical diluting segment of the ascending limb of Henle�s loop of the nephron.

Chlorthalidone Indications and Usage

Diuretics such as chlorthalidone are indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension.

Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis and corticosteroid and estrogen therapy.

Chlorthalidone has also been found useful in edema due to various forms of renal dysfunction such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.

Item No.: RX114348 NDC No.51079005820 UPC No.:351079058202 NDC No. 51079-0058-20 UPC/GTIN No. 3-51079-05820-2 MPN No. 5820 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L
Rx Item-Chlorthalidone 25mg Tab 100 By M
Item No.: RX114348 NDC No.51079005820 UPC No.:351079058202 NDC No. 51079-0058-20 UPC/GTIN No. 3-51079-05820-2 MPN No. 5820 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L

BRAND: CHLORTHALIDONE NDC: 51079-0058-20,51079005820 UPC: 3-51079-05820-2,351079058202 Mylan Institutional/Pgn
Chlorthalidone 25Mg Tab 100 By Mylan Ins
BRAND: CHLORTHALIDONE NDC: 51079-0058-20,51079005820 UPC: 3-51079-05820-2,351079058202 Mylan Institutional/Pgn

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
CHLORTHALIDONE ORAL TABLE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.