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Rx Item-Chlorhexidine 0.12% Liquid 16 oz By Akorn Pharma

Item No.: RX457176 NDC No.50383072016 UPC No.:350383720164 NDC No. 50383-0720-16 UPC/GTIN No. 3-50383-72016-4 MPN No. 72016 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.BRAND: CHLORHEXIDINE GLUCONATE NDC: 50383-0720-16,50383072016 UPC: 3-50383-72016-4,350383720164 Akorn IncOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Chlorhexidine 0.12% Liquid 16 oz By Akorn Pharma

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Item No.: RX457176 NDC No.50383072016 UPC No.:350383720164 NDC No. 50383-0720-16 UPC/GTIN No. 3-50383-72016-4 MPN No. 72016 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order RX Item. RX Item No. RX457176 Chlorhexidine 0.12% Liquid 16 oz By Akorn Pharma Item No. 3457176 NDC No. 50383072016 UPC No. 350

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PERIDEX- chlorhexidine gluconate rinse
3M ESPE Dental Products

DESCRIPTION

Peridex� (Chlorhexidine Gluconate 0.12%) Oral Rinse is an oral rinse containing 0.12% chlorhexidine gluconate (1, 11 -hexamethylene bis [5-(p-chlorophenyl) biguanide] di-D-gluconate) in a base containing water, 11.6% alcohol, glycerin, PEG-40 sorbitan diisostearate, flavor, sodium saccharin, and FD&C Blue No. 1. Peridex is a near-neutral solution (pH range 5-7). Chlorhexidine gluconate is a salt of chlorhexidine and gluconic acid. Its chemical structure is:

Chemical Structure
(click image for full-size original)
CLINICAL PHARMACOLOGY



Peridex provides antimicrobial activity during oral rinsing. The clinical significance of Peridex�s antimicrobial activities is not clear. Microbiological sampling of plaque has shown a general reduction of counts of certain assayed bacteria, both aerobic and anaerobic, ranging from 54-97% through six months use.

Use of Peridex in a six month clinical study did not result in any significant changes in bacteria resistance, overgrowth of potentially opportunistic organisms or other adverse changes in the oral microbial ecosystem. Three months after Peridex use was discontinued, the number of bacteria in plaque had returned to baseline levels and resistance of plaque bacteria to chlorhexidine gluconate was equal to that at baseline.

Pharmacokinetics
Pharmacokinetic studies with Peridex indicate approximately 30% of the active ingredient, chlorhexidine gluconate, is retained in the oral cavity following rinsing. This retained drug is slowly released into the oral fluids. Studies conducted on human subjects and animals demonstrate chlorhexidine gluconate is poorly absorbed from the gastrointestinal tract. The mean plasma level of chlorhexidine gluconate reached a peak of 0.206 mcg/g in humans 30 minutes after they ingested a 300-mg dose of the drug. Detectable levels of chlorhexidine gluconate were not present in the plasma of these subjects 12 hours after the compound was administered. Excretion of chlorhexidine gluconate occurred primarily through the feces (~90%). Less than 1% of the chlorhexidine gluconate ingested by these subjects was excreted in the urine.

INDICATIONS AND USAGE

Peridex is indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. Peridex has not been tested among patients with acute necrotizing ulcerative gingivitis (ANUG). For patients having coexisting gingivitis and periodontitis, see PRECAUTIONS.

Item No.: RX457176 NDC No.50383072016 UPC No.:350383720164 NDC No. 50383-0720-16 UPC/GTIN No. 3-50383-72016-4 MPN No. 72016 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.
Rx Item-Chlorhexidine 0.12% Liquid 16 oz
Item No.: RX457176 NDC No.50383072016 UPC No.:350383720164 NDC No. 50383-0720-16 UPC/GTIN No. 3-50383-72016-4 MPN No. 72016 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.

BRAND: CHLORHEXIDINE GLUCONATE NDC: 50383-0720-16,50383072016 UPC: 3-50383-72016-4,350383720164 Akorn Inc
Chlorhexidine 0.12% Liq 16 Oz By Akorn P
BRAND: CHLORHEXIDINE GLUCONATE NDC: 50383-0720-16,50383072016 UPC: 3-50383-72016-4,350383720164 Akorn Inc

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
CHLORHEXIDINE GLUCONATE M
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.