Rx Item-Cefpodoxime Proxetil 200mg Tab 20 By Sandoz Pharma

CEFPODOXIME PROXETIL- cefpodoxime proxetil tablet, film coated
Sandoz Inc

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Cefpodoxime Proxetil Tablets, USP and other antibacterial drugs, Cefpodoxime Proxetil Tablets, USP should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

For Oral Use Only

DESCRIPTION

Cefpodoxime proxetil is an orally administered, extended spectrum, semi-synthetic antibiotic of the cephalosporin class. The chemical name is (RS)-1(isopropoxycarbonyloxy) ethyl (+)-(6R,7R)-7-[2-(2-amino-4-thiazolyl)-2-{(Z)methoxyimino} acetamido]-3-methoxymethyl-8-oxo-5-thia-1-azabicyclo [4.2.0]oct-2-ene-2-carboxylate.



Its empirical formula is C21 H27 N5 O9 S2 and its structural formula is represented below:

Cefpodoxime Chemical Structure
(click image for full-size original)
The molecular weight of cefpodoxime proxetil is 557.6.

Cefpodoxime proxetil is a prodrug; its active metabolite is cefpodoxime. All doses of cefpodoxime proxetil in this insert are expressed in terms of the active cefpodoxime moiety. The drug is supplied as film-coated tablets.

Cefpodoxime Proxetil Tablets, USP contain cefpodoxime proxetil equivalent to 100 mg or 200 mg of cefpodoxime activity. Each film-coated tablet contains the following inactive ingredients: carboxymethylcellulose calcium, crospovidone, FD&C Yellow No. 6, hydroxypropyl cellulose, hypromellose, lactose monohydrate, magnesium stearate, sodium lauryl sulfate, talc and titanium dioxide.

CLINICAL PHARMACOLOGY

Absorption and Excretion
Cefpodoxime proxetil is a prodrug that is absorbed from the gastrointestinal tract and de-esterified to its active metabolite, cefpodoxime. Following oral administration of 100 mg of cefpodoxime proxetil to fasting subjects, approximately 50% of the administered cefpodoxime dose was absorbed systemically. Over the recommended dosing range (100 to 400 mg), approximately 29 to 33% of the administered cefpodoxime dose was excreted unchanged in the urine in 12 hours. There is minimal metabolism of cefpodoxime in vivo.

Rx Item-Cefpodoxime Proxetil 200mg Tab 2
Item No.: RX164475 NDC No.781543920 UPC No.:307815439201 NDC No. 00781-5439-20 UPC/GTIN No. 3-07815-43920-1 MPN No. 543920 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L

Cefpodoxime Proxetil 200Mg Tab 20 By San
BRAND: CEFPODOXIME PROXETIL NDC: 00781-5439-20,781543920 UPC: 3-07815-43920-1,307815439201 Sandoz/Rx

CEFPODOXIME PROXETIL ORAL
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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