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Rx Item-Cefoxitin 10 gm Vial 10 By Sagent Pharma

Item No.: RX006597 NDC No.25021011199 UPC No.:325021111994 NDC No. 25021-0111-99 UPC/GTIN No. 3-25021-11199-4 MPN No. 11199 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.BRAND: CEFOXITIN NDC: 25021-0111-99,25021011199 UPC: 3-25021-11199-4,325021111994 Sagent Pharmaceuticals, IncOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Cefoxitin 10 gm Vial 10 By Sagent Pharma

$1008.99$649.99

Item No.: RX006597 NDC No.25021011199 UPC No.:325021111994 NDC No. 25021-0111-99 UPC/GTIN No. 3-25021-11199-4 MPN No. 11199 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order RX Item. RX Item No. RX006597 Cefoxitin 10 gm Vial 10 By Sagent Pharma Item No. 3006597 NDC No. 25021011199 UPC No. 32502111199

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CEFOXITIN- cefoxitin sodium injection, powder, for solution
West-Ward Pharmaceuticals Corp


Rx Only

To reduce the development of drug-resistant bacteria and maintain the effectiveness of cefoxitin for injection and other antibacterial drugs, cefoxitin for injection should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

DESCRIPTION

Cefoxitin for injection is a semi-synthetic, broad-spectrum cepha antibiotic sealed under nitrogen for intravenous administration. It is derived from cephamycin C, which is produced by Streptomyces lactamdurans. Its chemical name is sodium (6R,7S)-3-(hydroxymethyl)-7-methoxy-8-oxo-7-[2-(2-thienyl)acetamido]-5-thia-1-azabicyclo [4.2.0] oct-2-ene-2-carboxylate carbamate (ester).



The molecular formula is C16 H16 N3 NaO7 S2 , and the structural formula is:

Chemical structure
(click image for full-size original)
Cefoxitin for injection contains approximately 53.8 mg (2.3 milliequivalents) of sodium per gram of cefoxitin activity. Solutions of cefoxitin for injection range from colorless to light amber in color. The pH of freshly constituted solutions usually ranges from 4.2 to 7.0. Cefoxitin for Injection, USP contains sterile cefoxitin sodium, USP equivalent to 1 or 2 grams cefoxitin.

CLINICAL PHARMACOLOGY

Clinical Pharmacology
Following an intravenous dose of 1 gram, serum concentrations were 110 mcg/mL at 5 minutes, declining to less than 1 mcg/mL at 4 hours. The half-life after an intravenous dose is 41 to 59 minutes. Approximately 85 percent of cefoxitin is excreted unchanged by the kidneys over a 6-hour period, resulting in high urinary concentrations. Probenecid slows tubular excretion and produces higher serum levels and increases the duration of measurable serum concentrations.

Cefoxitin passes into pleural and joint fluids and is detectable in antibacterial concentrations in bile. In a published study of geriatric patients ranging in age from 64 to 88 years with normal renal function for their age (creatinine clearance ranging from 31.5 to 174 mL/min), the half-life of cefoxitin ranged from 51 to 90 minutes, resulting in higher plasma concentrations than in younger adults. These changes were attributed to decreased renal function associated with the aging process.

Microbiology
Mechanism of Action
Cefoxitin is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Cefoxitin has activity in the presence of some beta-lactamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria.

Item No.: RX006597 NDC No.25021011199 UPC No.:325021111994 NDC No. 25021-0111-99 UPC/GTIN No. 3-25021-11199-4 MPN No. 11199 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.
Rx Item-Cefoxitin 10 gm Vial 10 By Sagen
Item No.: RX006597 NDC No.25021011199 UPC No.:325021111994 NDC No. 25021-0111-99 UPC/GTIN No. 3-25021-11199-4 MPN No. 11199 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.

BRAND: CEFOXITIN NDC: 25021-0111-99,25021011199 UPC: 3-25021-11199-4,325021111994 Sagent Pharmaceuticals, Inc
Cefoxitin 10 Gm Vial 10 By Sagent Pharma
BRAND: CEFOXITIN NDC: 25021-0111-99,25021011199 UPC: 3-25021-11199-4,325021111994 Sagent Pharmaceuticals, Inc

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
CEFOXITIN SODIUM INTRAVEN
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.