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Rx Item-Caverject 20mcg Vial 6 By Pfizer Pharma

Item No.: RX728881 NDC No.9370105 UPC No.:300093701052 NDC No. 00009-3701-05 UPC/GTIN No. 3-00093-70105-2 MPN No. 1895 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, BRAND: CAVERJECT NDC: 00009-3701-05,9370105 UPC: 3-00093-70105-2,300093701052 Pfizer PharmaceuticalOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Caverject 20mcg Vial 6 By Pfizer Pharma

$709.14$652.41

Item No.: RX728881 NDC No.9370105 UPC No.:300093701052 NDC No. 00009-3701-05 UPC/GTIN No. 3-00093-70105-2 MPN No. 1895 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order RX Item. RX Item No. RX728881 Caverject 20mcg Vial 6 By Pfizer Pharm Item No. 3728881 NDC No. 00009370105 UPC No. 300093701052 Other

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CAVERJECT- alprostadil injection, powder, lyophilized, for solution
Pharmacia and Upjohn Company LLC


For Intracavernosal Use

DESCRIPTION

CAVERJECT Sterile Powder contains alprostadil as the naturally occurring form of prostaglandin E1 (PGE1 ) and is designated chemically as (11?,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid. The molecular weight is 354.49.

Alprostadil is a white to off-white crystalline powder with a melting point between 115° and 116° C. Its solubility at 35° C is 8000 micrograms per 100 milliliter double distilled water. CAVERJECT is available as a sterile freeze-dried powder for intracavernosal use in four sizes: 5, 10, 20 and 40 micrograms per vial When reconstituted as directed with 1 milliliter of bacteriostatic water for injection or sterile water, both preserved with benzyl alcohol 0.945% w/v, gives 1.13 milliliters of reconstituted solution. Each milliliter of CAVERJECT contains 5.4, 10.5, 20.5 or 41.1 micrograms of alprostadil depending on vial strength, 172 milligrams of lactose, 47 micrograms of sodium citrate and 8.4 milligrams of benzyl alcohol. The deliverable amount of alprostadil is 5, 10, 20 or 40 micrograms per milliliter because approximately 0.4 microgram for the 5 microgram strength, 0.5 microgram for the 10 and 20 microgram strengths and 1.1 microgram for the 40 microgram strength is lost due to adsorption to the vial and syringe. When necessary, the pH of alprostadil for injection was adjusted with hydrochloric acid and/or sodium hydroxide before lyophilization.



The structural formula of alprostadil is represented below:

Chemical StructureChemical StructureFigureFigureFigureFigureFigureFigureFigureFigureFigureLogo
CLINICAL PHARMACOLOGY

Alprostadil has a wide variety of pharmacological actions; vasodilation and inhibition of platelet aggregation are among the most notable of these effects. In most animal species tested, alprostadil relaxed retractor penis and corpus cavernosum urethrae in vitro. Alprostadil also relaxed isolated preparations of human corpus cavernosum and spongiosum, as well as cavernous arterial segments contracted by either noradrenaline or PGF2? in vitro. In pigtail monkeys (Macaca nemestrina), alprostadil increased cavernous arterial blood flow in vivo. The degree and duration of cavernous smooth muscle relaxation in this animal model was dose-dependent.

Alprostadil induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries. This leads to expansion of lacunar spaces and entrapment of blood by compressing the venules against the tunica albuginea, a process referred to as the corporal veno-occlusive mechanism.

Item No.: RX728881 NDC No.9370105 UPC No.:300093701052 NDC No. 00009-3701-05 UPC/GTIN No. 3-00093-70105-2 MPN No. 1895 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab,
Rx Item-Caverject 20mcg Vial 6 By Pfizer
Item No.: RX728881 NDC No.9370105 UPC No.:300093701052 NDC No. 00009-3701-05 UPC/GTIN No. 3-00093-70105-2 MPN No. 1895 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab,

BRAND: CAVERJECT NDC: 00009-3701-05,9370105 UPC: 3-00093-70105-2,300093701052 Pfizer Pharmaceutical
Caverject 20Mcg Vial 6 By Pfizer Pharma
BRAND: CAVERJECT NDC: 00009-3701-05,9370105 UPC: 3-00093-70105-2,300093701052 Pfizer Pharmaceutical

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
ALPROSTADIL INTRACAVER VI
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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