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Rx Item-Capex (F&S) 0.01% Shampoo 4 oz By Galderma Labs

Item No.: RX075820 NDC No.299550004 UPC No.:302995500047 NDC No. 00299-5500-04 UPC/GTIN No. 3-02995-50004-7 MPN No. 550004 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.LBRAND: CAPEX NDC: 00299-5500-04,299550004 UPC: 3-02995-50004-7,302995500047 Galderma Labs Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Capex (F&S) 0.01% Shampoo 4 oz By Galderma Labs

$737.99$508.99

Item No.: RX075820 NDC No.299550004 UPC No.:302995500047 NDC No. 00299-5500-04 UPC/GTIN No. 3-02995-50004-7 MPN No. 550004 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order RX Item. RX Item No. RX075820 Capex (F&S) 0.01% Shm 4 oz By Galderma Labs, Item No. 3075820 NDC No. 00299550004 UPC No. 30299550

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CAPEX - fluocinolone acetonide
Galderma Laboratories, L.P.


DESCRIPTION:

Capex� Shampoo 0.01% is supplied as a shampoo formulation with a 12 mg fluocinolone acetonide capsule which is emptied into the shampoo base by the pharmacist at the time of dispensing. After mixing, Capex� Shampoo contains fluocinolone acetonide(6?,9-Difluoro-11?,16?, 17,21-tetrahydroxypregna-1,4-diene-3, 20-dione cyclic 16,17-acetal with acetone), a synthetic fluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and antipruritic agents.



Chemically, Capex� Shampoo mixture is C24 H30 F2 O6 . It has the following structural formula:

p52306-1-capex-chem-struct
(click image for full-size original)
Fluocinolone acetonide in Capex� Shampoo has the molecular weight of 452.50. It is a white crystalline powder that is odorless, stable in light and melts at 270�F with decomposition; soluble in alcohol, acetone and methanol; slightly soluble in chloroform; insoluble in water.

Each fluocinolone capsule contains 12 mg of fluocinolone acetonide, 548 mg of dibasic calcium phosphate dihydrate USP, and 240 mg of talc USP. The shampoo base contains aluminum acetate dibasic, benzalkonium chloride solution, boric acid, citric acid anhydrous, cocamido-ether-sulfate complex, cocoamine oxide, lauramide DEA, magnesium aluminum silicate, methylparaben, oat flour, propylene glycol, propylparaben, purified water, and fragrances, with D&C Yellow #10 and FD&C Blue #1 as coloring.

CLINICAL PHARMACOLOGY:

Like other topical corticosteroids, fluocinolone acetonide has anti-inflammatory, antipruritic and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2 .

Pharmacokinetics: The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle and the integrity of the epidermal barrier. Occlusive dressings with hydrocortisone for up to 24 hours have not been demonstrated to increase penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances penetration. Topical corticosteroids can be absorbed from normal intact skin while inflammation and/or other disease processes in the skin increase percutaneous absorption.

Capex� Shampoo is in the low to medium range of potency as compared with other topical corticosteroids.

Item No.: RX075820 NDC No.299550004 UPC No.:302995500047 NDC No. 00299-5500-04 UPC/GTIN No. 3-02995-50004-7 MPN No. 550004 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L
Rx Item-Capex (F&S) 0.01% Shampoo 4 oz B
Item No.: RX075820 NDC No.299550004 UPC No.:302995500047 NDC No. 00299-5500-04 UPC/GTIN No. 3-02995-50004-7 MPN No. 550004 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.L

BRAND: CAPEX NDC: 00299-5500-04,299550004 UPC: 3-02995-50004-7,302995500047 Galderma Labs
Capex (F&S) 0.01% Shampoo 4 Oz By Galder
BRAND: CAPEX NDC: 00299-5500-04,299550004 UPC: 3-02995-50004-7,302995500047 Galderma Labs

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
FLUOCINOLONE ACETONIDE TO
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.