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Caffeine 100% Pwd 500gm by Harvard Drug Group

NDC 62991-2015-02 UPC/GTIN No.3-62991-20152-2 Mfg.Part No.201502Harvard Drug GroupThis Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).Harvard Drug GroupImage 4 of Caffeine 100% Pwd 500gm by Harvard Drug Group

Caffeine 100% Pwd 500gm by Harvard Drug Group

$487.50$47.99

NDC No. 62991-2015-02 UPC/GTIN No. 3-62991-20152-2 MPN 201502 Only Physician,Pharmacy or Licensed Facility can order this Rx Item No. Rx119032 Caffeine 100% Pwd 500gm by Harvard Drug Group Item No. 3119032 NDC No. 62991201502 UPC No. 362991201522 Other Name Cafcit,Caffeine Citrate Therapeutic Code 282032 Therapeutic Class Respiratory And Cns Stimulants Item Class Non Controlled Rx. Case Qnty: 1 Therapeutic Code 282032 Respiratory And Cns Stimulants Info Central Nervous System Stimulant [Epc],Cen

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CAFCIT- caffeine citrate injection
CAFCIT- caffeine citrate solution
Bedford Laboratories

Rx ONLY

DESCRIPTION

Both CAFCIT® (caffeine citrate) Injection for intravenous administration and CAFCIT® (caffeine citrate) Oral Solution are clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solutions adjusted to pH 4.7. Each mL contains 20 mg caffeine citrate (equivalent to 10 mg of caffeine base) prepared in solution by the addition of 10 mg caffeine anhydrous to 5.0 mg citric acid monohydrate, 8.3 mg sodium citrate dihydrate and Water for Injection.



Caffeine, a central nervous system stimulant, is an odorless white crystalline powder or granule, with a bitter taste. It is sparingly soluble in water and ethanol at room temperature. The chemical name of caffeine is 3,7-dihydro-1,3,7-trimethyl-1H -purine-2,6-dione. In the presence of citric acid it forms caffeine citrate salt in solution. The structural formula and molecular weight of caffeine citrate follows.

structural formula
(click image for full-size original)
Caffeine citrate

C14 H18 N4 O9 Mol. Wt. 386.31

CLINICAL PHARMACOLOGY

Mechanism of Action
Caffeine is structurally related to other methylxanthines, theophylline, and theobromine. It is a bronchial smooth muscle relaxant, a CNS stimulant, a cardiac muscle stimulant, and a diuretic.

Although the mechanism of action of caffeine in apnea of prematurity is not known, several mechanisms have been hypothesized. These include: (1) stimulation of the respiratory center, (2) increased minute ventilation, (3) decreased threshold to hypercapnia, (4) increased response to hypercapnia, (5) increased skeletal muscle tone, (6) decreased diaphragmatic fatigue, (7) increased metabolic rate, and (8) increased oxygen consumption.

Most of these effects have been attributed to antagonism of adenosine receptors, both A1 and A2 subtypes, by caffeine, which has been demonstrated in receptor binding assays and observed at concentrations approximating those achieved therapeutically.

NDC 62991-2015-02 UPC/GTIN No.3-62991-20152-2 Mfg.Part No.201502
Caffeine 100% Pwd 500gm by Harvard Drug
NDC 62991-2015-02 UPC/GTIN No.3-62991-20152-2 Mfg.Part No.201502

Harvard Drug Group

Harvard Drug Group

This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).
CAFFEINE MISCELL POWDER 1
This Item Can Only Be Ordered By A Drug Mfg, Wholesaler,Pharmacy,Physician, Dentist, Podiatrist, Optometrist,Veterinarian,Naturopath,Licensed Lab, Physical Therapist & Pharmacist(scope).

Harvard Drug Group
Harvard Drug Group

Image 4 of Caffeine 100% Pwd 500gm by Harvard Drug Group