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Rx Item-Brimonidine Tartrate 0.2% drops 5ml by Sandoz Falcon Pharma

NDC No. 61314-0143-05 UPC/GTIN No. 3-61314-14305-1 MPN 14305 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical TherapSandoz/Falcon Pharma LtdOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Brimonidine Tartrate 0.2% drops 5ml by Sandoz Falcon Pharma

$32.65$15.98

Item No.:RX750707/a, Item No. RX750707, 750707, NDC No.: 61314-0143-05, 61314-143-05, 6131414305, 61314014305, 0143-05, 014305 UPC No. 3-61314-14305-1, 361314-143051, 361314143051, Rx Item-Brimonidine Tartrate 0.2% drops 5ml by Sandoz Falcon Pharma Only Physician, Pharmacy Or Licensed Facility Can purchase this RX Item Brand/Generic: , Drug Category: Ophthalmology--Anti GlaucomaDrug Class: 52400400 Alpha- Adrenergic Agonists (Eent)

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BRIMONIDINE TARTRATE OPHTHALMIC SOLUTION, 0.2%- brimonidine tartrate solution/ drops
Westminster Pharmaceuticals, LLC

PACKAGE LABEL PRINCIPAL DISPLAY PANEL

Brimonidine Tartrate
(click image for full-size original)
CLINICAL PHARMACOLOGY



Mechanism of Action:

Brimonidine Tartrate Ophthalmic Solution, 0.2% is an alpha adrenergic receptor agonist. It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric studies in animals and humans suggest that brimonidine tartrate has a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow.

Pharmacokinetics:

After ocular administration of a 0.2% solution, plasma concentrations peaked within 1 to 4 hours and declined with a systemic half-life of approximately 3 hours. In humans, systemic metabolism of brimonidine is extensive. It is metabolized primarily by the liver. Urinary excretion is the major route of elimination of the drug and its metabolites. Approximately 87% of an orally- administered radioactive dose was eliminated within 120 hours, with 74% found in the urine.

Clinical Evaluations:

Elevated IOP presents a major risk factor in glaucomatous field loss. The higher the level of IOP, the greater the likelihood of optic nerve damage and visual field loss. Brimonidine tartrate has the action of lowering intraocular pressure with minimal effect on cardiovascular and pulmonary parameters.

In comparative clinical studies with timolol 0.5%, lasting up to one year, the IOP lowering effect of Brimonidine Tartrate Ophthalmic Solution, 0.2% was approximately 4 � 6 mmHg compared with approximately 6 mmHg for timolol. In these studies, both patient groups were dosed BID; however, due to the duration of action of Brimonidine Tartrate Ophthalmic Solution, 0.2%; it is recommended that Brimonidine Tartrate Ophthalmic Solution, 0.2% be dosed TID. Eight percent of subjects were discontinued from studies due to inadequately controlled intraocular pressure, which in 30% of these patients occurred during the first month of therapy. Approximately 20% were discontinued due to adverse experiences.

INDICATIONS & USAGE

Brimonidine Tartrate Ophthalmic Solution, 0.2% is indicated for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The IOP lowering efficacy of Brimonidine Tartrate Ophthalmic Solution, 0.2% diminishes over time in some patients. This loss of effect appears with a variable time of onset in each patient and should be closely monitored.

NDC No. 61314-0143-05 UPC/GTIN No. 3-61314-14305-1 MPN 14305 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therap
Brimonidine Tartrate 0.2% drops 5ml by S
NDC No. 61314-0143-05 UPC/GTIN No. 3-61314-14305-1 MPN 14305 Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therap

Sandoz/Falcon Pharma Ltd
AmericanPharmaWholesale.com
Sandoz/Falcon Pharma Ltd

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
BRIMONIDINE TARTRATE OPHT
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.