SE BPO WASH- benzoyl peroxide solution
Seton Pharmaceuticals
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
Rx Only.
FOR EXTERNAL USE ONLY.
DESCRIPTION
SE BPO 5.5% Cream and SE BPO 7% Wash are topical preparations containing benzoyl peroxide as the active ingredient incorporated into a Novasome� system composed of lipid vesicles.
Ingredients for SE BPO 5.5% Cream include:
allantoin, aloe vera gel, butylene glycol, caprylic/capric triglyceride, cetearyl alcohol, cetearyl glucoside, cetearyl olivate, cetyl alcohol, dimethicone, disodium EDTA, ethylene/acrylic acid copolymer, glycerin, glycine soya (soybean) sterols, methylparaben, phenoxyethanol, propylparaben, purified water, sorbitan olivate, stearyl alcohol, tocopheryl acetate, and xanthan gum.
Ingredients for SE BPO 7% Wash include:
C12-C15 alkyl benzoate, cholesterol, citric acid, cocamidopropyl betaine, cocamine oxide, dimethicone, disodium laureth sulfosuccinate, edetate disodium, fragrance, glycerin, glyceryl stearate, hydrogenated castor oil, hypromellose, magnesium aluminum silicate, magnesium chloride, magnesium nitrate, methylchloroisothiazolinone, methylisothiazolinone, methylparaben, nonoxynol-20, octoxynol-5, PEG-6 caprylic/capric glycerides, PEG-15 pentaerythrityl tetrastearate, PEG-40 hydrogenated castor oil, poloxamer 182, purified water, sodium cocoate, and xanthan gum.
Benzoyl peroxide is an oxidizing agent that possesses antibacterial properties and is classified as a keratolytic. Benzoyl peroxide (C14 H10 O4 ) is represented by the following structure:
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CLINICAL PHARMACOLOGY
The exact method of action of benzoyl peroxide in acne vulgaris is not known. Benzoyl peroxide is an antibacterial agent with demonstrated activity against Propionibacterium acnes. This action, combined with the mild keratolytic effect of benzoyl peroxide is believed to be responsible for its usefulness in acne. Benzoyl peroxide is absorbed by the skin where it is metabolized to benzoic acid and excreted as benzoate in the urine.
INDICATIONS AND USAGE
SE BPO 5.5% Cream and SE BPO 7% Wash are indicated for use in the topical treatment of mild to moderate acne vulgaris.
