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Rx Item-Aminophylline 500mg 20ml Vial 25X20ml By Hospira Worldwide

NDC No.00409-5922-01 UPC/GTIN No.3-04095-92201-9 MPN No. 592201 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PAHospira Worldwide Inc.Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Aminophylline 500mg 20ml Vial 25X20ml By Hospira Worldwide

$341.37$318.93

NDC No.00409-5922-01 UPC/GTIN No.3-04095-92201-9 MPN No. 592201 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Rx Item No.Rx165910 Aminophylline 500Mg/20ml Vial 25X20ml By Hospira Worldwide Item No.3165910 NDC No.00409592201 UPC No.304095922019 Other Name: Aminophylline Therapeutic Code 8

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AMINOPHYLLINE- aminophylline injection, solution
AMERICAN REGENT LABORATORIES, INC.
Aminophylline
Aminophylline is 2:1 complex of theophylline and ethylenediamine. Theophylline is structurally classified as methylxanthine. Aminophylline occurs as white or slightly yellowish granule or powder, with slight ammoniacal odor. Aminophylline has the chemical name 1H-Purine-2,6-dione,3,7-dihydro-1,3-dimethyl-, compound with 1,2-ethanediamine (2:1
The molecular formula of anhydrous aminophylline is C16 H24 N10 O4 with molecular weight of 420.43.
Each mL contains: Aminophylline (calculated as the dihydrate) 25 mg (equivalent to 19.7 mg of anhydrous theophylline), and is intended for intravenous administration.
Inactive Ingredients:
Ethylenediamine ???????.. 3.74 mg
Water for Injection ?????????? q.s.
The pH is between 8.6 and 9.0.
CLINICAL PHARMACOLOGY
Mechanism of Action:
Theophylline has two distinct actions in the airways of patients with reversible obstruction; smooth muscle relaxation (i.e., bronchodilation) and suppression of the response of the airways to stimuli (i.e., non-bronchodilator prophylactic effects). While the mechanisms of action of theophylline are not known with certainty, studies in animals suggest that bronchodilatation is mediated by the inhibition of two isozymes of phosphodiesterase (PDE III and, to lesser extent, PDE IV) while non-bronchodilator prophylactic actions are probably mediated through one or more different molecular mechanisms, that do not involve inhibition of PDE III or antagonism of adenosine receptors. Some of the adverse effects associated with theophylline appear to be mediated by inhibition of PDE III (e.g., hypotension, tachycardia, headache, and emesis) and adenosine receptor antagonism (e.g., alterations in cerebral blood flow).
Theophylline increases the force of contraction of diaphragmatic muscles. This action appears to be due to enhancement of calcium uptake through an adenosine-mediated channel.
INDICATIONS AND USAGE
Intravenous theophylline is indicated as an adjunct to inhaled beta-2 selective agonists and systemically administered corticosteroids for the treatment of acute exacerbations of the symptoms and reversible airflow obstruction associated with asthma and other chronic lung diseases, e.g., emphysema and chronic bronchitis.
CONTRAINDICATIONS
Aminophylline Injection, USP is contraindicated in patients with history of hypersensitivity to theophylline or other components in the product: including ethylenediamine
DOSAGE AND ADMINISTRATION
General Considerations:
The steady-state serum theophylline concentration is function of the infusion rate and the rate of theophylline clearance in the individual patient. Because of marked individual differences in the rate of theophylline clearance, the dose required to achieve serum theophylline concentration in the 10-20 mcg/mL range varies four-fold among otherwise similar patients in the absence of factors known to alter theophylline clearance. For given population there is no single theophylline dose that will provide both safe and effective serum concentrations for all patients. Administration of the median theophylline dose required to achieve therapeutic serum theophylline concentration in given population may result in either sub-therapeutic or potentially toxic serum theophylline concentrations in individual patients. The dose of theophylline must be individualized on the basis of serum theophylline concentration measurements in order to achieve dose that will provide maximum potential benefit with minimal risk of adverse effects.
Aminophylline Injection, USP (25 mg/mL) is available as follows:
NDC 0517-3810-25
10 mL Single Dose Vial250 mg/10 mL (25 mg/mL)
Packed in boxes of 25
NDC 0517-3820-25
20 mL Single Dose Vial500 mg/20 mL (25 mg/mL)
Packed in boxes of 25
PROTECT FROM LIGHT. Keep vials in carton until time of use.
Store at controlled room temperature 15?-30?C (59?-86?F) (See USP).
Do not use if crystals are present.
SINGLE DOSE CONTAINER. Discard unused portion

NDC No.00409-5922-01 UPC/GTIN No.3-04095-92201-9 MPN No. 592201 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA
Rx Item-Aminophylline 500mg 20ml Vial 25
NDC No.00409-5922-01 UPC/GTIN No.3-04095-92201-9 MPN No. 592201 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA

Hospira Worldwide Inc.
AmericanPharmaWholesale.com
Hospira Worldwide Inc.

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
AMINOPHYLLINE
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.