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Rx Item-Altoprev Lovastatin 20mg Tab 30 By Covis Pharma

NDC No.59630-0628-30 UPC/GTIN No.3-59630-62830-7 MPN No. 62830 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA,Covis Pharmaceuticals IncOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Altoprev Lovastatin 20mg Tab 30 By Covis Pharma

$1299.77$1167.99

RX569330 569330 NDC No.59630-0628-30 70515-628-30 70515062830 7051562830 UPC/GTIN No.3-59630-62830-7 359630-628307 359630628307 MPN No. 62830 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Rx Item No.Rx426472 Altoprev 20mg Tab 30 By Covis Pharma Item No.3426472 NDC No.59630062830 UPC No.

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Clinical Information
Gen. Code and Des.
50556 lovastatin ORAL TAB ER 24H 20 MG
GCN and Des.
17651 lovastatin ORAL TAB ER 24H 20 MG
Strength
20MG ER
Dose Form
TABLET, EXTENDED RELEASE 24 HR
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
24060800 HMG-COA REDUCTASE INHIBITORS
Active Ingredients
2063 lovastatin 75330755
Inactive Ingredients
10143 yellow dye
2432 lactose 64044515
2598 sucrose 57501

ALTOPREV- lovastatin tablet, extended release
Shionogi Inc.
DESCRIPTION
Altoprev? lovastatin extended-release tablets contain cholesterol-lowering agent isolated from strain of Aspergillus terreus. After oral ingestion, lovastatin, which is an inactive lactone, is hydrolyzed to the corresponding ?-hydroxyacid form. This is principal metabolite and inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme (HMG-CoA) reductase. This enzyme catalyzes the conversion of HMG-CoA to mevalonate, which is an early and rate limiting step in the biosynthesis of cholesterol.
Lovastatin is [1 -[1?(R*),3?,7?,8?* ,4 S*),8a?]]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H -pyran-2-yl)ethyl]-1-naphthalenyl 2-methylbutanoate. The empirical formula of lovastatin is C24 H36 O5 and its molecular weight is 404.55.
Mechanism of Action
Lovastatin is lactone that is readily hydrolyzed in vivo to the corresponding ?-hydroxyacid, strong inhibitor of HMG-CoA reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonate. The conversion of HMG-CoA to mevalonate is an early step in the biosynthetic pathway for cholesterol
INDICATIONS AND USAGE
Therapy with lipid-altering agents should be one component of multiple risk factor intervention in individuals who require modifications of their lipid profile. Drug therapy is recommended as an adjunct to diet restricted in saturated fat and cholesterol only when the response to diet and other non-pharmacological measures has been inadequate.
Prevention of oronary Heart Disease
In patients without symptomatic coronary heart disease (CHD), but at high risk, Altoprev? is indicated to reduce the risk of:
Myocardial infarction

Unstable angina

Coronary revascularization procedures
Coronary Heart Disease
Altoprev? is indicated to slow the progression of coronary atherosclerosis in patients with coronary heart disease as part of treatment strategy to lower Total-C and LDL-C to target levels.
1.2 Hyperlipidemia
Altoprev? is indicated as an adjunct to diet for the reduction of elevated Total-C, LDL-C, Apo B, and TG, and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and non-familial) and mixed dyslipidemia (Fredrickson types IIa and IIb).
1. Limitations of Use
Altoprev? has not been studied in Fredrickson Types I, III, and V.
DOSAGE AND ADMINISTRATION
2.1 Hyperlipidemia (Heterozygous Familial and Nonfamilial) and Mixed Dyslipidemia (Fredrickson Types IIa and IIb)
The recommended dosing range is 20-60 mg/day, in single doses taken in the evening at bedtime.
Altoprev? (lovastatin extended-release) tablets are supplied as round, convex shaped tablets containing 20 mg, 40 mg and 60 mg of lovastatin.

NDC No.59630-0628-30 UPC/GTIN No.3-59630-62830-7 MPN No. 62830 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA,
Rx Item-Altoprev 20mg Tab 30 By Covis Ph
NDC No.59630-0628-30 UPC/GTIN No.3-59630-62830-7 MPN No. 62830 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA,

Covis Pharmaceuticals Inc
AmericanPharmaWholesale.com
Covis Pharmaceuticals Inc

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
LOVASTATIN ORAL TAB ER 24
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.