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Rx Item-Almotriptan 12.5mg Tab 12 By Mylan Pharma

NDC No.00378-5246-85 UPC/GTIN No.3-03785-24685-5 MPN No. 524685 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PAMylan PharmaOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Almotriptan 12.5mg Tab 12 By Mylan Pharma

$503.03$499.99

NDC No.00378-5246-85 UPC/GTIN No. 3-03785-24685-5 MPN No. 524685 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Rx Item No.Rx488767 Almotriptan 12.5mg Tab 12 By Mylan Pharma Item No.3488767 NDC No.00378524685 UPC No.303785246855 Other Name: Axert Oral Therapeutic Code 283228 Therapeutic C

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Almotriptan Malate:Axert
INDICATIONS AND USAGE
1.1 Acute Treatment of Migraine Attacks
Adults
Almotriptan tablets, USP are indicated for the acute treatment of migraine attacks in patients with history of migraine with or without aura.
Adolescents Age 12 to 17 Years
Almotriptan tablets, USP are indicated for the acute treatment of migraine headache pain in patients with history of migraine attacks with or without aura usually lasting hours or more (when untreated).
1.2 Important Limitations
Almotriptan tablets should only be used where clear diagnosis of migraine has been established. If patient has no response for the first migraine attack treated with almotriptan tablets, the diagnosis of migraine should be reconsidered before almotriptan tablets are administered to treat any subsequent attacks.
In adolescents age 12 to 17 years, efficacy of almotriptan tablets on migraine-associated symptoms (nausea, photophobia, and phonophobia) was not established. Almotriptan tablets are not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine [see Contraindications ].
Safety and effectiveness of almotriptan tablets have not been established for cluster headache which is present in an older, predominantly male population.
2 DOSAGE AND ADMINISTRATION
2.1 Acute Treatment of Migraine Attacks
The recommended dose of almotriptan tablets, USP in adults and adolescents age 12 to 17 years is 6.25 mg to 12.5 mg, with the 12.5 mg dose tending to be more effective dose in adults. As individuals may vary in their response to different doses of almotriptan tablets, the choice of dose should be made on an individual basis.
If the headache is relieved after the initial almotriptan tablets dose but returns, the dose may be repeated after hours. The effectiveness of second dose has not been established in placebo-controlled trials. The maximum daily dose should not exceed 25 mg. The safety of treating an average of more than four migraines in 30-day period has not been established.
2.2 Hepatic Impairment
The recommended starting dose of almotriptan tablets, USP in patients with hepatic impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over 24-hour period [see Warnings and Precautions and Clinical Pharmacology (12.3)].
2.3 Renal Impairment
The recommended starting dose of almotriptan tablets, USP in patients with severe renal impairment is 6.25 mg. The maximum daily dose should not exceed 12.5 mg over 24-hour period [see Warnings and Precautions and Clinical Pharmacology (12.3)].
3 DOSAGE FORMS AND STRENGTHS
Almotriptan tablets, USP are available as white, circular, biconvex, film-coated tablets in the following dosage strengths:
6.25 mg tablet debossed with ?A1? on one side and plain on other side.
12.5 mg tablet debossed with ?A2? on one side and plain on other side.
4 CONTRAINDICATIONS
4.1 Ischemic or Vasospastic Coronary Artery Disease, or Other Significant Underlying Cardiovascular Disease
Do not use almotriptan tablets in patients with ischemic heart disease (angina pectoris, history of myocardial infarction, or documented silent ischemia), or in patients who have symptoms or findings consistent with ischemic heart disease, coronary artery vasospasm, including Prinzmetal?s variant angina, or other significant underlying cardiovascular disease [see Warnings and Precautions ].
4.2 Cerebrovascular Syndromes
Do not use almotriptan tablets in patients with cerebrovascular syndromes including (but not limited to) stroke of any type as well as transient ischemic attacks [see Warnings and Precautions ].
4.3 Peripheral Vascular Disease
Do not use almotriptan tablets in patients with peripheral vascular disease including (but not limited to) ischemic bowel disease [see Warnings and Precautions ].
4.4 Uncontrolled Hypertension
Because almotriptan tablets may increase blood pressure, do not use almotriptan tablets in patients with uncontrolled hypertension [see Warnings and Precautions ].
4.5 ERgotamine-Containing and ERgot-Type Medications
Do not use almotriptan tablets and ergotamine-containing or ergot-derived medications like dihydroergotamine, ergotamine tartrate, or methysergide within 24 hours of each other [see Drug Interactions ].
4.6 Concomitant Use With 5-HT1 Agonists (e.g., Triptans)
Almotriptan tablets and other 5-HT1 agonists (e.g., triptans) should not be administered within 24 hours of each other [see Warnings and Precautions and ].
4.7 Hemiplegic or Basilar Migraine
Do not use almotriptan tablets in patients with hemiplegic or basilar migraine.
4.8 Hypersensitivity
Almotriptan tablets are contraindicated in patients with known hypersensitivity to almotriptan or any of its inactive ingredients.
Mechanism of Action
Almotriptan binds with high affinity to 5-HT1D 5-HT1B and 5-HT1F receptors. Almotriptan has weak affinity for 5-HT1A and 5-HT7 receptors, but has no significant affinity or pharmacological activity at 5-HT2 5-HT3 5-HT4 5-HT6 alpha or beta adrenergic; adenosine (A1 A2 ); angiotensin (AT1 AT2 ); dopamine (D1 D2 ); endothelin (ETA ETB ); or tachykinin (NK1 NK2 NK3 binding sites.


NDC No.00378-5246-85 UPC/GTIN No.3-03785-24685-5 MPN No. 524685 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA
Rx Item-Almotriptan 12.5mg Tab 12 By Myl
NDC No.00378-5246-85 UPC/GTIN No.3-03785-24685-5 MPN No. 524685 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA

Mylan Pharma
AmericanPharmaWholesale.com
Mylan Pharma

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
ALMOTRIPTAN MALATE ORAL T
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.