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Rx Item-Alimta 100mg Vial By Lilly Eli & Co

NDC No.00002-7640-01 UPC/GTIN No.3-00027-64001-3 MPN No. 00002-7640-01 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, PharmacLilly Eli & CoOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Alimta 100mg Vial By Lilly Eli & Co

$970.32$899.99

NDC No.00002-7640-01 UPC/GTIN No. 3-00027-64001-3 MPN No. 00002-7640-01 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Rx Item No.Rx773940 Alimta 100mg Vial By Lilly Eli & Co Item No.3773940 NDC No.00002764001 UPC No.300027640013 Other Name: Pemetrexed Disodium Inj IV Therapeutic Cla

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Clinical Information
Gen. Code and Des.
63546 pemetrexed disodium INTRAVEN VIAL 100 MG
GCN and Des.
99268 pemetrexed disodium INTRAVEN VIAL 100 MG
Strength
100MG
Dose Form
VIAL (EA)
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
10000000 ANTINEOPLASTIC AGENTS
Active Ingredients
8495 pemetrexed disodium 150399238
Inactive Ingredients
2272 mannitol 69658




Item info.
These highlights do not include all the info. needed to use
ALIMTA safely and effectively. See full prescribing info. for
ALIMTA.
ALIMTA (pemetrexed
for injection
), for Intravenous Use
Initial U.S. Approval: 2004
--
RECENT MAJOR CHANGES
-
Dosage and Administration, Premedication Regimen
and Concurrent
Medications

10/2012
Warnings and Precautions,
Requirement for Premedication and
Concomitant Medication to Reduce Toxicity

10/2012
Warnings and Precautions, Required Laboratory Monitoring
10/2012
-
INDICATIONS AND USAGE
--
ALIMTA
?
is folate analog metabolic inhibitor indicated for:
?
Locally Advanced or Metastatic Nonsquamou
s Non
-
Small Cell
Lung Cancer:
?
Initial treatment in combination with cisplatin.
?
Maintenance treatment of patients whose disease has not
progressed after four cycles of platinum
-
based first
-
line
chemotherapy.
?
After prior chemotherapy as s
ingle
-
agent.
?
Mesothelioma: in combination with cisplatin.
Limitations of Use:
?
ALIMTA is not indicated for the treatment of patients with
squamous cell non
-
small cell lung cancer.

DOSAGE AND ADMINISTRATION
-
?
Combination use in Non
-
Small Cell Lung Cancer and
Mesothelioma: Recommended dose of ALIMTA is 500
mg/m
2
i.v.
on Day of each 21
-
day cycle in combination with cisplatin
75
mg/m
2
i.v. beginning 30
minutes after ALIMTA administration.

?
Single
-
Agent use in Non
-
Small Cell Lun
g Cancer: Recommended
dose of ALIMTA is 500
mg/m
2
i.v. on Day
1 of each 21
-
day cycle.

?
Prior to initiating ALIMTA, initiate supplementation with oral folic
acid and intramuscular vitamin
B
12
. Continue folic acid and
vitamin
B
12
supplementation throu
ghout treatment. Administer
corticosteroids the day before, the day of, and the day after
ALIMTA administration.
?
Dose Reductions: Dose reductions or discontinuation may be
needed based on toxicities from the preceding cycle of therapy.

--
DOSAG
E FORMS AND STRENGTHS
-
?
100
mg vial for injection
?
500
mg vial for injection
-
CONTRAINDICATIONS

History of severe hypersensitivity reaction to pemetrexed.

WARNINGS AND PRECAUTIONS
-
?
Premedication regimen:
Prior
to
treatment with ALIMTA, in
itiate
supplementation with oral
folic acid and
intramuscular
vitamin
B
12
to reduce the severity of hematologic and gastrointestinal toxicity
of ALIMTA
.
?
Bone marrow suppression: Reduce doses for subsequent cycles
based on hematologic and
nonhematologic toxicities.
?
Renal function: Do not administer when CrCl <45
mL/min. (2.4,
5.3)
?
NSAIDs with renal insufficiency: Use caution in patients with mild
to moderate renal insufficiency (CrCl 45
-
79
mL/min).
?
Lab monitoring: Do not
i
nitiate a
cycle unless ANC
?
1500
cells/mm
3
, platelets
?
100,000
cells/mm
3
, and CrCl
?
45
mL/min.
?
Pregnancy: Fetal harm can occur when administered to
pregnant woman. W
omen should be advised to use effective
contraception measures to prevent pregnan
cy during treatment
with ALIMTA.
-
ADVERSE REACTIONS

The most common adverse reactions (incidence
?
20%) with single
-
agent use are fatigue, nausea, and anorexia. Additional common
adverse reactions when used in combination with cisplatin include
vomit
ing, neutropenia, leukopenia, anemia, stomatitis/pharyngitis,
thrombocytopenia, and constipation.
To report SUSPECTED ADVERSE REACTIONS, contact Eli Lilly
and Company at 1
-
800
-
LillyRx (1
-
800
-
545
-
5979) or FDA at 1
-
800
-
FDA
-
1088 or www.fda.gov/medwatch.
-
DRUG INTERACTIONS

?
NSAIDs: Use caution with NSAIDs.
?
Nephrotoxic drugs: Concomitant use of these drugs and/or
substances which are tubularly secreted may result in delayed
clearance.
See 17 for PATIENT COUNSELING info. and FDA
-
approv
ed patient label

NDC No.00002-7640-01 UPC/GTIN No.3-00027-64001-3 MPN No. 00002-7640-01 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmac
Rx Item-Alimta 100mg Vial By Lilly Eli &
NDC No.00002-7640-01 UPC/GTIN No.3-00027-64001-3 MPN No. 00002-7640-01 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmac

Lilly Eli & Co
AmericanPharmaWholesale.com
Lilly Eli & Co

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
PEMETREXED DISODIUM INTRA
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Want to do Research on this Med or need a large quantity? Email Details with quantity required to:[email protected]

Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
AmericanPharmaWholesale.com
Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.