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Rx Item-Aldactazide 25Mg/25mg Tab 100 By Pfizer Pharma

NDC No. 00025-1011-31 UPC/GTIN No. 3-00251-01131-3 MPN No. 2134 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PAPfizer PharmaceuticalOnly Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scopWant to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.comVisit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.

Rx Item-Aldactazide 25Mg/25mg Tab 100 By Pfizer Pharma

$324.99$319.99

RX255992 255992
NDC No. 00025-1011-31 UPC/GTIN No. 3-00251-01131-3 MPN No. 2134 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA, Physical Therapist, Podiatrist, Research Co., Uni., VA, Vet & Wholesalers In Scope Of their Practice Can Order Rx Item. Rx Item No. Rx255992 Aldactazide 25Mg/25mg Tab 100 By Pfizer Pharm Item No. 3255992 NDC No. 00025101131 UPC No. 300251011313 Other Name Spironolactone And Hydroc

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Clinical Information
Gen. Code and Des.
6813 spironolact/hydrochlorothiazid ORAL TABLET 25 MG-25MG
GCN and Des.
82330 spironolact/hydrochlorothiazid ORAL TABLET 25 MG-25MG
Strength
25/25MG
Dose Form
TABLET
Product Category
RX Pharmaceuticals
Fine Line Class
850085008510 All Rx Products
DEA Class
NC
OMP Family

AHFS Class
24322000 MINERALOCORTICOID (ALDOSTERONE) ANTAGNTS
40281600 POTASSIUM-SPARING DIURETICS
24082416 POTASSIUM-SPARING DIURETICS (HYPOTEN)
24082420 THIAZIDE DIURETICS(HYPOTENSIVE AGENTS)
24084420 MINERALOCORTICOID(ALDOSTER.)ANTAG(HYPOT)
40282000 THIAZIDE DIURETICS
Active Ingredients
2211 spironolactone 52017
2294 hydrochlorothiazide 58935
Inactive Ingredients
2537 povidone 9003398






ALDACTAZIDE- spironolactone and hydrochlorothiazide tablet, film coated
G.D. Searle LLC Division of Pfizer Inc
WARNING
Spironolactone, an ingredient of ALDACTAZIDE, has been shown to be tumorigen in chronic toxicity studies in rats (see Precautions). ALDACTAZIDE should be used only in those conditions described under Indications and USAge. Unnecessary use of this drug should be avoided.
Fixed-dose combination drugs are not indicated for initial therapy of edema or hypertension. Edema or hypertension requires therapy titrated to the individual patient. If the fixed combination represents the dosage so determined, its use may be more convenient in patient management. The treatment of hypertension and edema is not static but must be reevaluated as conditions in each patient warrant.
DESCRIPTION
ALDACTAZIDE oral tablets contain:
spironolactone . . . . . . . . . . 25 mg
hydrochlorothiazide . . . . . . . . 25 mg
or
spironolactone . . . . . . . . . . 50 mghydrochlorothiazide . . . . . . . . 50 mg
Spironolactone (ALDACTONE?), an aldosterone antagonist, is 17-hydroxy-7?-mercapto-3-oxo-17?-pregn-4-ene-21-carboxylic acid ?-lactone acetate
Spironolactone is practically insoluble in water, soluble in alcohol, and freely soluble in benzene and in chloroform.
Hydrochlorothiazide, diuretic and antihypertensive, is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
Hydrochlorothiazide is slightly soluble in water and freely soluble in sodium hydroxide solution.
Inactive ingredients include calcium sulfate, corn starch, flavor, hydroxypropyl cellulose, hypromellose, iron oxide, magnesium stearate, polyethylene glycol, povidone, and titanium dioxide.
Mechanism of action
ALDACTAZIDE is combination of two diuretic agents with different but complementary mechanisms and sites of action, thereby providing additive diuretic and antihypertensive effects. Additionally, the spironolactone component helps to minimize the potassium loss characteristically induced by the thiazide component.
The diuretic effect of spironolactone is mediated through its action as specific pharmacologic antagonist of aldosterone, primarily by competitive binding of receptors at the aldosterone-dependent sodium-potassium exchange site in the distal convoluted renal tubule. Hydrochlorothiazide promotes the excretion of sodium and water primarily by inhibiting their reabsorption in the cortical diluting segment of the distal renal tubule.
ALDACTAZIDE is indicated for:
Edematous conditions for patients with:
Congestive heart failure:
Cirrhosis of the liver accompanied by edema and/or ascites:
The nephrotic syndrome:
Essential hypertension:
CONTRAINDICATIONS
ALDACTAZIDE is contraindicated in patients with anuria, acute renal insufficiency, significant impairment of renal excretory function, hypercalcemia, hyperkalemia, Addison?s disease, and in patients who are allergic to thiazide diuretics or to other sulfonamide-derived drugs. ALDACTAZIDE may also be contraindicated in acute or severe hepatic failure.


NDC No. 00025-1011-31 UPC/GTIN No. 3-00251-01131-3 MPN No. 2134 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA
Rx Item-Aldactazide 25Mg/25mg Tab 100 By
NDC No. 00025-1011-31 UPC/GTIN No. 3-00251-01131-3 MPN No. 2134 Only Lic.-Physician, Pharmacy, Dentist, Drug Mfg, Dist., Gov, Hospital, Lic.Lab, Naturalist, Naturopath, NP, Optometrist, Pharmacist, PA

Pfizer Pharmaceutical
AmericanPharmaWholesale.com
Pfizer Pharmaceutical

Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop
Click avove for SPIRONOLACTONE/HYDROCHLO
Only Lic.-Physician,Pharmacy,Dentist,Drug Mfg,Dist.,Gov,Hospital,Lic.Lab,Naturalist,Naturopath,NP,Optometrist,Pharmacist,PA,Physical Therapist,Podiatrist,Research Co.,Uni.,VA,Vet & Wholesalers in scop

Want to do Research on this Med or need a large quantity? Email Details with quantity required to:sales@AmericanPharmaWholesale.com
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.
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Visit AmericanPharmaWholesale.com for over 100,000 items of Health & Beauty at Retail@Wholesale prices.